Younghwa J. Na

Pocheon-si, Republic of Korea

Last Updated: 09/26/2026

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Found 66 publications

Discovery of a Small-Molecule Inhibitor Targeting the ELF3-HSP27 Interaction to Suppress Breast Cancer Progression.

Discovery of a Small-Molecule Inhibitor Targeting the ELF3-HSP27 Interaction to Suppress Breast Cancer Progression.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: April 16, 2026

KN21, a direct AMPK activator, alleviates hepatic steatosis and fibrosis by modulating long-chain TAG and pyrimidine metabolism in a MASH mouse model.

KN21, a direct AMPK activator, alleviates hepatic steatosis and fibrosis by modulating long-chain TAG and pyrimidine metabolism in a MASH mouse model.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 08, 2025

Modulation of AMPK/NLRP3 Signaling Mitigates Radiation-Induced Lung Inflammation by a Synthetic Lipoxin A4 Analogue.

Modulation of AMPK/NLRP3 Signaling Mitigates Radiation-Induced Lung Inflammation by a Synthetic Lipoxin A4 Analogue.

Journal: International journal of molecular sciences

Published: July 07, 2025

Pharmacological Activation of AMP-activated Protein Kinase Ameliorates Liver Fibrosis in a Metabolic Dysfunction-Associated Steatohepatitis Mouse Model.

Pharmacological Activation of AMP-activated Protein Kinase Ameliorates Liver Fibrosis in a Metabolic Dysfunction-Associated Steatohepatitis Mouse Model.

Journal: International journal of biological sciences

Published: December 13, 2024

Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction.

Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction.

Journal: eLife

Published: December 06, 2024

Computer-aided discovery of novel AMPK activators through virtual screening and SAR-driven synthesis.

Computer-aided discovery of novel AMPK activators through virtual screening and SAR-driven synthesis.

Journal: European journal of medicinal chemistry

Published: November 13, 2024

Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer.

Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer.

Journal: Molecular cancer

Published: October 19, 2024

The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer.

The Nα-acetyl-L-lysine/Loxl2/H2O2 promotes intestinal tumor growth in Drosophila and cell proliferation in human colorectal cancer.

Journal: Cell reports

Published: August 11, 2024

Calpain 2 Isoform-Specific Cleavage of Filamin A Enhances HIF1α Nuclear Translocation, Promoting Metastasis in Triple-Negative Breast Cancer.

Calpain 2 Isoform-Specific Cleavage of Filamin A Enhances HIF1α Nuclear Translocation, Promoting Metastasis in Triple-Negative Breast Cancer.

Journal: MedComm

Published: July 30, 2024

Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple-negative breast cancer cells.

Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple-negative breast cancer cells.

Journal: Cancer science

Published: October 18, 2023

Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis.

Drug like HSP27 cross linkers with chromenone structure ameliorates pulmonary fibrosis.

Journal: Frontiers in pharmacology

Published: April 10, 2023

Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells.

Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells.

Journal: European journal of medicinal chemistry

Published: November 21, 2022

Showing 1-12 of 66

Last Updated: 09/26/2026