Yu-hong Chen

State Key Laboratory Of Multi Organ Injury Prevention And Treatment, Guangdong Provincial Key Laboratory Of Precision Medicine For Gastrointestinal Tumor
Guangzhou, China

Last Updated: 09/26/2026

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Found 21 publications

Targeting PTPN13 with 11-amino-acid peptides of C-terminal APC prevents immune evasion of colorectal cancer.

Targeting PTPN13 with 11-amino-acid peptides of C-terminal APC prevents immune evasion of colorectal cancer.

Journal: Cell research
Published: May 07, 2025

AAK1 activation-mediated iron trafficking drives ferroptotic cell death.

AAK1 activation-mediated iron trafficking drives ferroptotic cell death.

Journal: Nature communications
Published: April 21, 2025

Susceptibility of Mitophagy-Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation.

Susceptibility of Mitophagy-Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: October 08, 2024

Reactivating cGAS-STING Signaling by Targeting SOS1 Enhances Antitumor Immunity in NRAS-Mutant Tumors.

Reactivating cGAS-STING Signaling by Targeting SOS1 Enhances Antitumor Immunity in NRAS-Mutant Tumors.

Journal: Cancer research
Published: August 18, 2024

Targeting site-specific N-glycosylated B7H3 induces potent antitumor immunity.

Targeting site-specific N-glycosylated B7H3 induces potent antitumor immunity.

Journal: Nature communications
Published: August 04, 2024

Galectin-13 reduces membrane localization of SLC7A11 for ferroptosis propagation.

Galectin-13 reduces membrane localization of SLC7A11 for ferroptosis propagation.

Journal: Nature chemical biology
Published: July 10, 2024

TRPML1 triggers ferroptosis defense and is a potential therapeutic target in AKT-hyperactivated cancer.

TRPML1 triggers ferroptosis defense and is a potential therapeutic target in AKT-hyperactivated cancer.

Journal: Science translational medicine
Published: June 26, 2024

Inactivated cGAS-STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2- Breast Cancer.

Inactivated cGAS-STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2- Breast Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: April 06, 2024

Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis.

Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis.

Journal: Redox biology
Published: December 26, 2022

CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.

CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.

Journal: Autophagy
Published: May 12, 2021

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis.

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis.

Journal: Nature cell biology
Published: April 29, 2021

MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis.

MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis.

Journal: Autophagy
Published: November 20, 2020
Showing 1-12 of 21

Last Updated: 09/26/2026