Yu-wei Lin

Guangdong Provincial Key Laboratory Of New Drug Design And Evaluation
Guangzhou, 510006, China

Last Updated: 09/26/2026

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Found 9 publications

A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis.

A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis.

Journal: Acta pharmaceutica Sinica. B

Published: September 03, 2025

Identification of Indoquinazoline Derivatives as Novel NR4A1 Agonists by Suppressing Adipocyte Lipogenesis for Treatment of Obesity.

Identification of Indoquinazoline Derivatives as Novel NR4A1 Agonists by Suppressing Adipocyte Lipogenesis for Treatment of Obesity.

Journal: Journal of medicinal chemistry

Published: August 15, 2025

HSQC-guided discovery and structural optimization of antiadipogenic indole diterpenoids from endophytic fungus Penicillium janthinellum H-6.

HSQC-guided discovery and structural optimization of antiadipogenic indole diterpenoids from endophytic fungus Penicillium janthinellum H-6.

Journal: European journal of medicinal chemistry

Published: May 23, 2025

Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes.

Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes.

Journal: Cellular signalling

Published: July 29, 2024

L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure.

L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure.

Journal: Diabetes, obesity & metabolism

Published: July 25, 2024

Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.

Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.

Journal: Journal of medicinal chemistry

Published: July 12, 2024

Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents.

Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents.

Journal: European journal of medicinal chemistry

Published: July 02, 2024

Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism.

Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism.

Journal: European journal of medicinal chemistry

Published: July 12, 2023

Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA.

Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA.

Journal: Molecules (Basel, Switzerland)

Published: February 17, 2023

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Last Updated: 09/26/2026