Yueming Zheng

State Key Laboratory Of Drug Research
Shanghai, China

Last Updated: 09/26/2026

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Found 22 publications

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid-Onset Antidepressant Agent in Mice.

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid-Onset Antidepressant Agent in Mice.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: May 24, 2025

The host susceptibility/resistance-related genes and gut microbial characteristics in Salmonella pullorum-infected chickens.

The host susceptibility/resistance-related genes and gut microbial characteristics in Salmonella pullorum-infected chickens.

Journal: Microbiology spectrum

Published: March 03, 2025

Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties.

Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties.

Journal: European journal of medicinal chemistry

Published: February 06, 2025

Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy.

Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy.

Journal: Journal of medicinal chemistry

Published: July 22, 2024

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels.

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels.

Journal: Journal of ethnopharmacology

Published: February 02, 2024

Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain.

Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain.

Journal: European journal of medicinal chemistry

Published: March 08, 2023

Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.

Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.

Journal: Nature chemical biology

Published: February 06, 2023

Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel.

Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel.

Journal: Acta pharmacologica Sinica

Published: November 18, 2022

Dynamics of Small Non-coding RNA Profiles and the Intestinal Microbiome of High and Low Weight Chickens.

Dynamics of Small Non-coding RNA Profiles and the Intestinal Microbiome of High and Low Weight Chickens.

Journal: Frontiers in microbiology

Published: April 09, 2022

Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators.

Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators.

Journal: Bioorganic chemistry

Published: March 08, 2022

Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors.

Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors.

Journal: Frontiers in pharmacology

Published: March 02, 2022

SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs.

SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs.

Journal: Acta pharmacologica Sinica

Published: February 26, 2022

Showing 1-12 of 22

Last Updated: 09/26/2026