Yuge Zhu

Key Laboratory Of Carcinogenesis And Translational Research
Beijing, China

Last Updated: 09/26/2026

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Found 10 publications

Redirecting Cholesterol Metabolism During Ex Vivo Biomanufacturing Enhances the Metabolic Fitness and Antitumor Efficacy of CAR-T Cells.

Redirecting Cholesterol Metabolism During Ex Vivo Biomanufacturing Enhances the Metabolic Fitness and Antitumor Efficacy of CAR-T Cells.

Journal: International journal of biological sciences
Published: January 27, 2026

MMP3 overexpression enhances CAR-T cell infiltration and antitumor activity in a CAF-enriched solid tumor model.

MMP3 overexpression enhances CAR-T cell infiltration and antitumor activity in a CAF-enriched solid tumor model.

Journal: Journal for immunotherapy of cancer
Published: December 09, 2025

Overcoming stromal resistance in solid tumors with MMP2-engineered CAR-T cells.

Overcoming stromal resistance in solid tumors with MMP2-engineered CAR-T cells.

Journal: Pharmacological research
Published: November 11, 2025

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling.

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling.

Journal: Frontiers in immunology
Published: September 02, 2025

Optimization of hinge domain enhances antitumor efficacy of globo H-targeted CAR-T cells in solid tumor models.

Optimization of hinge domain enhances antitumor efficacy of globo H-targeted CAR-T cells in solid tumor models.

Journal: iScience
Published: August 12, 2025

Integrating Bulk and Single-Cell Transcriptomics with Machine Learning Reveals a Heme Metabolism-Based Panel for Lung Adenocarcinoma Chemotherapy Resistance.

Integrating Bulk and Single-Cell Transcriptomics with Machine Learning Reveals a Heme Metabolism-Based Panel for Lung Adenocarcinoma Chemotherapy Resistance.

Journal: International journal of molecular sciences
Published: March 24, 2025

Multi‑omics analysis identifies different molecular subtypes with unique outcomes in early-stage poorly differentiated lung adenocarcinoma.

Multi‑omics analysis identifies different molecular subtypes with unique outcomes in early-stage poorly differentiated lung adenocarcinoma.

Journal: Molecular cancer
Published: February 22, 2025

NKG2D/CD28 chimeric receptor boosts cytotoxicity and durability of CAR-T cells for solid and hematological tumors.

NKG2D/CD28 chimeric receptor boosts cytotoxicity and durability of CAR-T cells for solid and hematological tumors.

Journal: Experimental hematology & oncology
Published: January 04, 2025

The role of dynamic monitoring of plasma cell-free DNA methylation in predicting pathological response in resectable stage IIB-IIIB non-small cell lung cancer: biomarker analyses from a prospective phase II trial.

The role of dynamic monitoring of plasma cell-free DNA methylation in predicting pathological response in resectable stage IIB-IIIB non-small cell lung cancer: biomarker analyses from a prospective phase II trial.

Journal: BMC medicine
Published: October 27, 2024

Membrane-bound IL-7 immobilized by the CD8 transmembrane region improves efficacy of CD19 CAR-T cell therapy.

Membrane-bound IL-7 immobilized by the CD8 transmembrane region improves efficacy of CD19 CAR-T cell therapy.

Journal: Molecular cancer
Published: September 05, 2024
Showing 1-10 of 10

Last Updated: 09/26/2026