Yukari Sagae

Kyoto, Japan

Last Updated: 09/26/2026

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Found 14 publications

Functional Analysis of a Novel Pathogenic Glycine Amidinotransferase Mutant in Hereditary Fanconi Syndrome.

Functional Analysis of a Novel Pathogenic Glycine Amidinotransferase Mutant in Hereditary Fanconi Syndrome.

Journal: Kidney medicine
Published: March 05, 2026

Mutation of CMTR2 in Lung Adenocarcinoma Alters RNA Alternative Splicing and Reveals Therapeutic Vulnerabilities.

Mutation of CMTR2 in Lung Adenocarcinoma Alters RNA Alternative Splicing and Reveals Therapeutic Vulnerabilities.

Journal: Nature communications
Published: January 27, 2025

A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.

A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer.

Journal: NPJ precision oncology
Published: November 06, 2023

LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion.

LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion.

Journal: Communications biology
Published: June 08, 2023

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.

Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.

Journal: Cancer research
Published: March 12, 2022

Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test.

Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test.

Journal: Cellular oncology (Dordrecht, Netherlands)
Published: December 03, 2021

Sensitivity to dabrafenib and trametinib treatments in patients with non-small-cell cancer harboring BRAF compound mutations: A pooled analysis of BRAF p.V600E-positive advanced non-small-cell lung cancer.

Sensitivity to dabrafenib and trametinib treatments in patients with non-small-cell cancer harboring BRAF compound mutations: A pooled analysis of BRAF p.V600E-positive advanced non-small-cell lung cancer.

Journal: Cancer genetics
Published: May 20, 2021

Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics.

Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics.

Journal: Nature communications
Published: February 09, 2021

Novel Resistance Mechanisms Including L1196Q, P1094H, and R1248_D1249 Insertion in Three Patients With NSCLC After ALK Tyrosine Kinase Inhibitor Treatment.

Novel Resistance Mechanisms Including L1196Q, P1094H, and R1248_D1249 Insertion in Three Patients With NSCLC After ALK Tyrosine Kinase Inhibitor Treatment.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Published: September 04, 2020

Discovery of natural TRPA1 activators through pharmacophore-based virtual screening and a biological assay.

Discovery of natural TRPA1 activators through pharmacophore-based virtual screening and a biological assay.

Journal: Bioorganic & medicinal chemistry letters
Published: August 12, 2020

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.

Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer.

Journal: Nature communications
Published: May 14, 2020

Identification of a new class of non-electrophilic TRPA1 agonists by a structure-based virtual screening approach.

Identification of a new class of non-electrophilic TRPA1 agonists by a structure-based virtual screening approach.

Journal: Bioorganic & medicinal chemistry letters
Published: February 05, 2020
Showing 1-12 of 14

Last Updated: 09/26/2026