Yuki Domon

Hiromachi, 1408710, Japan

Last Updated: 09/26/2026

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Found 17 publications

N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors.

N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors.

Journal: ACS medicinal chemistry letters

Published: March 06, 2023

The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation.

The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation.

Journal: Drug research

Published: October 10, 2022

Improvement in social anxiety following a return-to-work intervention for patients with depression.

Improvement in social anxiety following a return-to-work intervention for patients with depression.

Journal: Medicine

Published: September 02, 2021

A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity.

A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity.

Journal: Bioorganic & medicinal chemistry letters

Published: September 23, 2020

Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity.

Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity.

Journal: Bioorganic & medicinal chemistry

Published: July 09, 2020

Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain.

Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain.

Journal: Chemical & pharmaceutical bulletin

Published: July 03, 2020

Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor.

Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor.

Journal: Journal of medicinal chemistry

Published: May 12, 2020

Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia.

Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia.

Journal: Pharmacological reports : PR

Published: January 28, 2020

Effects of mirogabalin, a novel ligand for the α₂δ subunit of voltage-gated calcium channels, on N-type calcium channel currents of rat dorsal root ganglion culture neurons.

Effects of mirogabalin, a novel ligand for the α₂δ subunit of voltage-gated calcium channels, on N-type calcium channel currents of rat dorsal root ganglion culture neurons.

Journal: Die Pharmazie

Published: April 10, 2019

Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity.

Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity.

Journal: Bioorganic & medicinal chemistry letters

Published: March 27, 2019

Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity.

Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity.

Journal: Bioorganic & medicinal chemistry letters

Published: March 13, 2019

Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia.

Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: November 25, 2018

Showing 1-12 of 17

Last Updated: 09/26/2026