Yuko Nabeshima

Sugitani, 9300914, Japan

Last Updated: 09/26/2026

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Found 23 publications

Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.

Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.

Journal: Journal of medicinal chemistry

Published: January 06, 2025

Divergent Total Synthesis of Isoflavone Natural Products and Their Potential as Therapeutic Agents for TTR Amyloidosis.

Divergent Total Synthesis of Isoflavone Natural Products and Their Potential as Therapeutic Agents for TTR Amyloidosis.

Journal: Journal of natural products

Published: October 27, 2024

SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+-binding pocket.

SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD+-binding pocket.

Journal: FEBS letters

Published: May 06, 2024

Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.

Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.

Journal: Journal of medicinal chemistry

Published: April 26, 2024

Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA.

Enzymatic activity of cGAS in the presence of three types of DNAs: limited cGAS stimulation by single-stranded HIV-1 SL2 DNA.

Journal: Bioscience reports

Published: February 28, 2024

Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.

Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin.

Journal: Journal of medicinal chemistry

Published: November 01, 2023

Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.

Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.

Journal: The FEBS journal

Published: August 06, 2023

Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity.

Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity.

Journal: Bioorganic & medicinal chemistry letters

Published: June 13, 2023

Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.

Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis.

Journal: Bioorganic & medicinal chemistry

Published: April 24, 2023

Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.

Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin.

Journal: The FEBS journal

Published: March 19, 2023

Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity.

Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity.

Journal: FEBS letters

Published: February 14, 2023

Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.

Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: January 18, 2023

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Last Updated: 09/26/2026