Yukun G. Zhang

Union Hospital
Wuhan, 430022, China

Last Updated: 09/26/2026

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Found 118 publications

Impaired Chaperone-Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation.

Impaired Chaperone-Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: May 21, 2026

Engineered senescence-targeting apoptotic extracellular vesicles-laden injectable hydrogel microspheres mitigating nucleus pulposus cell ferroptosis against intervertebral disc degeneration.

Engineered senescence-targeting apoptotic extracellular vesicles-laden injectable hydrogel microspheres mitigating nucleus pulposus cell ferroptosis against intervertebral disc degeneration.

Journal: Biomaterials
Published: April 22, 2026

A Challenge-Oriented Review of Delivery Systems for Cell and Gene Therapies in Intervertebral Disc Degeneration.

A Challenge-Oriented Review of Delivery Systems for Cell and Gene Therapies in Intervertebral Disc Degeneration.

Journal: Bioengineering (Basel, Switzerland)
Published: April 09, 2026

Correction: Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.

Correction: Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy.

Journal: Cell death & disease
Published: March 25, 2026

A sono-piezoelectric scaffold prompts disc regeneration by activating Ca2+/CaMKII/Parkin-mediated mitophagy.

A sono-piezoelectric scaffold prompts disc regeneration by activating Ca2+/CaMKII/Parkin-mediated mitophagy.

Journal: Biomaterials
Published: January 26, 2026

The role of NOTCH signaling pathway in intervertebral disc degeneration.

The role of NOTCH signaling pathway in intervertebral disc degeneration.

Journal: Tissue & cell
Published: November 27, 2025

Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.

Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.

Journal: Bioactive materials
Published: November 26, 2025

Corrigendum to "Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways" [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis., 1863 (2017) 1479-1491].

Corrigendum to "Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways" [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis., 1863 (2017) 1479-1491].

Journal: Biochimica et biophysica acta. Molecular basis of disease
Published: November 05, 2025

Advantages of 12° Endoscope in Unilateral Biportal Endoscopic Surgery for Lumbar Disc Herniation.

Advantages of 12° Endoscope in Unilateral Biportal Endoscopic Surgery for Lumbar Disc Herniation.

Journal: International journal of spine surgery
Published: October 06, 2025

Elevated TRIM25 Impairs Poly (ADP-ribose) Metabolism via PARG Degradation and Mediates Compression-Induced Intervertebral Disc Degeneration.

Elevated TRIM25 Impairs Poly (ADP-ribose) Metabolism via PARG Degradation and Mediates Compression-Induced Intervertebral Disc Degeneration.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: September 29, 2025

Prevalence, diagnosis, and clinical significance of lumbosacral transitional vertebrae: A systematic review and narrative analysis.

Prevalence, diagnosis, and clinical significance of lumbosacral transitional vertebrae: A systematic review and narrative analysis.

Journal: Brain & spine
Published: July 31, 2025

Ultrasound-responsive piezoelectric hydrogel attenuates oxidative stress-induced nucleus pulposus senescence via AMPK-FOXO1a-mediated mitophagy for intervertebral disc regeneration.

Ultrasound-responsive piezoelectric hydrogel attenuates oxidative stress-induced nucleus pulposus senescence via AMPK-FOXO1a-mediated mitophagy for intervertebral disc regeneration.

Journal: Biomaterials
Published: July 27, 2025
Showing 1-12 of 118

Last Updated: 09/26/2026