Yunhan Jiang

Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 15 publications

Repurposing indacaterol as a novel NETs inhibitor for the treatment of colorectal tumor metastasis.

Repurposing indacaterol as a novel NETs inhibitor for the treatment of colorectal tumor metastasis.

Journal: Biochemical pharmacology
Published: January 19, 2026

Universal Protein Trans-Splicing-Based CAR System Enabling CAR-T Cells with Reduced Exhaustion and Enhanced Efficacy.

Universal Protein Trans-Splicing-Based CAR System Enabling CAR-T Cells with Reduced Exhaustion and Enhanced Efficacy.

Journal: Journal of medicinal chemistry
Published: April 01, 2025

Design, synthesis, and biological evaluation of novel (E)-2-cyano-3-(4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-2-yl) derivatives as potent STAT3-targeting anticolorectal cancer agents.

Design, synthesis, and biological evaluation of novel (E)-2-cyano-3-(4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-2-yl) derivatives as potent STAT3-targeting anticolorectal cancer agents.

Journal: Bioorganic chemistry
Published: September 04, 2024

Advancing Tumor-Targeted Chemo-Immunotherapy: Development of the CAR-M-derived Exosome-Drug Conjugate.

Advancing Tumor-Targeted Chemo-Immunotherapy: Development of the CAR-M-derived Exosome-Drug Conjugate.

Journal: Journal of medicinal chemistry
Published: July 23, 2024

Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4+ T cell for inflammatory bowel diseases treatment.

Chemical activation of mitochondrial ClpP to modulate energy metabolism of CD4+ T cell for inflammatory bowel diseases treatment.

Journal: Cell reports. Medicine
Published: April 23, 2024

The U.S. FDA approved cardiovascular drugs from 2011 to 2023: A medicinal chemistry perspective.

The U.S. FDA approved cardiovascular drugs from 2011 to 2023: A medicinal chemistry perspective.

Journal: European journal of medicinal chemistry
Published: April 21, 2024

A novel theranostic strategy for myocardial infarction through neutralization of endogenous SO2 using an endoplasmic reticulum-targeted fluorescent probe.

A novel theranostic strategy for myocardial infarction through neutralization of endogenous SO2 using an endoplasmic reticulum-targeted fluorescent probe.

Journal: European journal of medicinal chemistry
Published: April 15, 2024

Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.

Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.

Journal: European journal of medicinal chemistry
Published: January 10, 2024

Strategies for the Discovery of Oxazolidinone Antibacterial Agents: Development and Future Perspectives.

Strategies for the Discovery of Oxazolidinone Antibacterial Agents: Development and Future Perspectives.

Journal: Journal of medicinal chemistry
Published: October 09, 2023

Facilitating the development of molecular glues: Opportunities from serendipity and rational design.

Facilitating the development of molecular glues: Opportunities from serendipity and rational design.

Journal: European journal of medicinal chemistry
Published: August 28, 2023

Discovery and SAR Study of Quinoxaline-Arylfuran Derivatives as a New Class of Antitumor Agents.

Discovery and SAR Study of Quinoxaline-Arylfuran Derivatives as a New Class of Antitumor Agents.

Journal: Pharmaceutics
Published: September 20, 2022

SAR Study and Molecular Mechanism Investigation of Novel Naphthoquinone-furan-2-cyanoacryloyl Hybrids with Antitumor Activity.

SAR Study and Molecular Mechanism Investigation of Novel Naphthoquinone-furan-2-cyanoacryloyl Hybrids with Antitumor Activity.

Journal: Pharmaceutics
Published: July 15, 2022
Showing 1-12 of 15

Last Updated: 09/26/2026