Yutaka Kitano
R&D Division
Tokyo, Japan
Tokyo, Japan
Last Updated: 09/26/2026
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Found 20 publications
Characterization of actions of the novel gabapentinoid drug mirogabalin on painful bladder hypersensitivity in rats with lipopolysaccharide-induced chronic cystitis.
Journal: Life sciences
Published: May 12, 2025
Mirogabalin inhibits scratching behavior of spontaneous model mouse of atopic dermatitis.
Journal: Frontiers in pharmacology
Published: February 05, 2024
N-Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors.
Journal: ACS medicinal chemistry letters
Published: March 06, 2023
Voltage-gated calcium channel subunit α2δ-1 in spinal dorsal horn neurons contributes to aberrant excitatory synaptic transmission and mechanical hypersensitivity after peripheral nerve injury.
Journal: Frontiers in molecular neuroscience
Published: November 16, 2022
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit.
Journal: Journal of molecular biology
Published: October 30, 2022
The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation.
Journal: Drug research
Published: October 10, 2022
Inhibition of NaV1.7: the possibility of ideal analgesics.
Journal: RSC medicinal chemistry
Published: March 09, 2022
Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an experimental model of fibromyalgia.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: February 15, 2021
Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain.
Journal: Chemical & pharmaceutical bulletin
Published: July 03, 2020
Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor.
Journal: Journal of medicinal chemistry
Published: May 12, 2020
Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia.
Journal: Pharmacological reports : PR
Published: January 28, 2020
Effects of mirogabalin, a novel ligand for the α₂δ subunit of voltage-gated calcium channels, on N-type calcium channel currents of rat dorsal root ganglion culture neurons.
Journal: Die Pharmazie
Published: April 10, 2019
Last Updated: 09/26/2026