Yutong Tu
Zhongshan, 528400, China
Last Updated: 09/26/2026
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Found 8 publications
Design, Synthesis, and Structure-Activity Relationship Studies of 7H‑Pyrrolo[2,3‑d]pyrimidine Derivatives as Potent Casein Kinase 1α (CK1α) Inhibitors.
Journal: ACS medicinal chemistry letters
Published: October 22, 2025
Discovery of a selective CDK7 PROTAC against acute leukemia with low platelet toxicity.
Journal: Leukemia
Published: September 27, 2025
DiPTAC: A degradation platform via directly targeting proteasome.
Journal: Acta pharmaceutica Sinica. B
Published: May 31, 2024
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors.
Journal: ACS medicinal chemistry letters
Published: January 25, 2024
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins.
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins.
Journal: Bioorganic chemistry
Published: November 03, 2023
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia.
Journal: Leukemia
Published: November 16, 2022
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment.
Journal: European journal of medicinal chemistry
Published: December 06, 2021
Showing 1-8 of 8
Last Updated: 09/26/2026