Yuxin Chen

Key Laboratory Of Marine Drugs, 5 Yushan Road
Qingdao, 266003, China

Last Updated: 09/26/2026

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Found 33 publications

Design, synthesis, and anti-inflammatory evaluation of novel N-(Benzol[d]oxazol-5-yl)sulfonamides as NLRP3 inflammasome inhibitors.

Design, synthesis, and anti-inflammatory evaluation of novel N-(Benzol[d]oxazol-5-yl)sulfonamides as NLRP3 inflammasome inhibitors.

Journal: Bioorganic chemistry

Published: February 15, 2026

Design, Synthesis, and Anti-inflammatory Activity Evaluation for Hydrazide-Based HDAC6 Targeted Protein Degraders.

Design, Synthesis, and Anti-inflammatory Activity Evaluation for Hydrazide-Based HDAC6 Targeted Protein Degraders.

Journal: Journal of medicinal chemistry

Published: November 11, 2025

Breaking the activity-selectivity trade-off in Fenton-like catalysis by d-orbital modulation of single-atom sites within a nano-island-like structure.

Breaking the activity-selectivity trade-off in Fenton-like catalysis by d-orbital modulation of single-atom sites within a nano-island-like structure.

Journal: Nature communications

Published: October 30, 2025

Design, synthesis, and biological evaluation of novel HDAC3 PROTACs for combined therapy with Venetoclax in acute myeloid leukemia.

Design, synthesis, and biological evaluation of novel HDAC3 PROTACs for combined therapy with Venetoclax in acute myeloid leukemia.

Journal: Bioorganic chemistry

Published: September 03, 2025

Development of Hydrazide-Based HDAC6 Selective Inhibitors for Treating NLRP3 Inflammasome-Related Diseases.

Development of Hydrazide-Based HDAC6 Selective Inhibitors for Treating NLRP3 Inflammasome-Related Diseases.

Journal: Journal of medicinal chemistry

Published: April 07, 2025

Discovery of hydrazide-based PI3K/HDAC dual inhibitors with enhanced pro-apoptotic activity in lymphoma cells.

Discovery of hydrazide-based PI3K/HDAC dual inhibitors with enhanced pro-apoptotic activity in lymphoma cells.

Journal: European journal of medicinal chemistry

Published: February 12, 2025

Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13.

Design, synthesis, and anti-cancer evaluation of the novel conjugate of gemcitabine's ProTide prodrug based on CD13.

Journal: Bioorganic chemistry

Published: January 13, 2025

Design, synthesis, and biological activity evaluation of novel HDAC3 selective inhibitors for combination with Venetoclax against acute myeloid leukemia.

Design, synthesis, and biological activity evaluation of novel HDAC3 selective inhibitors for combination with Venetoclax against acute myeloid leukemia.

Journal: European journal of medicinal chemistry

Published: May 08, 2024

Discovery of novel biphenyl-sulfonamide analogues as NLRP3 inflammasome inhibitors.

Discovery of novel biphenyl-sulfonamide analogues as NLRP3 inflammasome inhibitors.

Journal: Bioorganic chemistry

Published: January 02, 2024

Discovery of benzamide-based PI3K/HDAC dual inhibitors with marked pro-apoptosis activity in lymphoma cells.

Discovery of benzamide-based PI3K/HDAC dual inhibitors with marked pro-apoptosis activity in lymphoma cells.

Journal: European journal of medicinal chemistry

Published: August 01, 2023

Laparoscopic Double Hepatic Artery Banding/Ligation for Patients With Hepatic Hereditary Haemorrhagic Telangiectasia (HHHT).

Laparoscopic Double Hepatic Artery Banding/Ligation for Patients With Hepatic Hereditary Haemorrhagic Telangiectasia (HHHT).

Journal: EJVES vascular forum

Published: March 16, 2023

Tannic acid-crosslinked O-carboxymethyl chitosan hydrogels for enhanced antibacterial activity and rapid hemostasis.

Tannic acid-crosslinked O-carboxymethyl chitosan hydrogels for enhanced antibacterial activity and rapid hemostasis.

Journal: Journal of biomaterials science. Polymer edition

Published: August 11, 2022

Showing 1-12 of 33

Last Updated: 09/26/2026