Yuxin Ye

Guangzhou, 510515, China

Last Updated: 09/26/2026

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Found 20 publications

Stigmasterol-Mediated Targeting of Rho-Associated Coiled-Coil Protein Kinase 1 Ameliorates Diabetic Kidney Disease and Attenuates Renal Tubular Lipid Deposition.

Stigmasterol-Mediated Targeting of Rho-Associated Coiled-Coil Protein Kinase 1 Ameliorates Diabetic Kidney Disease and Attenuates Renal Tubular Lipid Deposition.

Journal: Biomaterials research

Published: February 05, 2026

A Unified Peptide Generative Framework via a Weakly Order-Dependent Autoregressive Language Model and Lifelong Learning.

A Unified Peptide Generative Framework via a Weakly Order-Dependent Autoregressive Language Model and Lifelong Learning.

Journal: Journal of chemical information and modeling

Published: August 01, 2025

Elucidating Binding Selectivity in Cyclin-Dependent Kinases 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors.

Elucidating Binding Selectivity in Cyclin-Dependent Kinases 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors.

Journal: Journal of medicinal chemistry

Published: January 04, 2025

In-Depth Structural Analysis of a Stapled Pentapeptide and Its Assembly Into Straight α-Helices.

In-Depth Structural Analysis of a Stapled Pentapeptide and Its Assembly Into Straight α-Helices.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: July 23, 2024

Intramolecular CH⋯π attraction mediated conformational polymorphism of constrained helical peptides.

Intramolecular CH⋯π attraction mediated conformational polymorphism of constrained helical peptides.

Journal: Chemical science

Published: April 17, 2024

Structural insights into the biochemical mechanism of the E2/E3 hybrid enzyme UBE2O.

Structural insights into the biochemical mechanism of the E2/E3 hybrid enzyme UBE2O.

Journal: Structure (London, England : 1993)

Published: November 12, 2023

Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region.

Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region.

Journal: Journal of medicinal chemistry

Published: November 03, 2023

A pyridinium-based strategy for lysine-selective protein modification and chemoproteomic profiling in live cells.

A pyridinium-based strategy for lysine-selective protein modification and chemoproteomic profiling in live cells.

Journal: Chemical science

Published: October 30, 2023

The S1'-S3' Pocket of the SARS-CoV-2 Main Protease Is Critical for Substrate Selectivity and Can Be Targeted with Covalent Inhibitors.

The S1'-S3' Pocket of the SARS-CoV-2 Main Protease Is Critical for Substrate Selectivity and Can Be Targeted with Covalent Inhibitors.

Journal: Angewandte Chemie (International ed. in English)

Published: July 07, 2023

Protective Role of Endothelial SIRT1 in Deep Vein Thrombosis and Hypoxia-induced Endothelial Dysfunction Mediated by NF-κB Deacetylation.

Protective Role of Endothelial SIRT1 in Deep Vein Thrombosis and Hypoxia-induced Endothelial Dysfunction Mediated by NF-κB Deacetylation.

Journal: Inflammation

Published: February 16, 2023

Chemo-Selective Cys-Pen Disulfide for Proximity-Induced Cysteine Cross-Linking.

Chemo-Selective Cys-Pen Disulfide for Proximity-Induced Cysteine Cross-Linking.

Journal: ACS chemical biology

Published: February 28, 2022

Aqueous extract of Paeoniae Radix Rubra prevents deep vein thrombosis by ameliorating inflammation through inhibiting GSK3β activity.

Aqueous extract of Paeoniae Radix Rubra prevents deep vein thrombosis by ameliorating inflammation through inhibiting GSK3β activity.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: June 26, 2021

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Last Updated: 09/26/2026