Yuyan Zhang

NHC Key Laboratory Of Microbial Drugs, State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College, Tiantan Xili 1#
Beijing, China

Last Updated: 09/26/2026

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Found 8 publications

Novel aromatic amide Pan-PPAR agonists for dual amelioration of hepatic steatosis and islet dysfunction by promoting cholesterol efflux in the KKAy diabetic mice.

Novel aromatic amide Pan-PPAR agonists for dual amelioration of hepatic steatosis and islet dysfunction by promoting cholesterol efflux in the KKAy diabetic mice.

Journal: European journal of medicinal chemistry

Published: April 23, 2026

Novel SIRT1 up-regulator F1462 attenuates endothelial cell senescence and vascular aging by promoting mitochondrial biogenesis via activating the SIRT1/PGC-1α/TFAM pathway.

Novel SIRT1 up-regulator F1462 attenuates endothelial cell senescence and vascular aging by promoting mitochondrial biogenesis via activating the SIRT1/PGC-1α/TFAM pathway.

Journal: European journal of pharmacology

Published: April 03, 2026

A Novel RANKL/RANK Inhibitor IMB-R38 Inhibits Osteoporosis Through Regulating Bone Metabolism.

A Novel RANKL/RANK Inhibitor IMB-R38 Inhibits Osteoporosis Through Regulating Bone Metabolism.

Journal: International journal of molecular sciences

Published: October 10, 2025

A Multimodal CMOS Readout IC for SWIR Image Sensors with Dual-Mode BDI/DI Pixels and Column-Parallel Two-Step Single-Slope ADC.

A Multimodal CMOS Readout IC for SWIR Image Sensors with Dual-Mode BDI/DI Pixels and Column-Parallel Two-Step Single-Slope ADC.

Journal: Micromachines

Published: May 27, 2025

The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.

The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.

Journal: Bioorganic chemistry

Published: January 14, 2024

A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue.

A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: September 13, 2023

SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism.

SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism.

Journal: Current issues in molecular biology

Published: April 21, 2023

Amplification-Free Detection of SARS-CoV-2 Down to Single Virus Level by Portable Carbon Nanotube Biosensors.

Amplification-Free Detection of SARS-CoV-2 Down to Single Virus Level by Portable Carbon Nanotube Biosensors.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: December 28, 2022

Showing 1-8 of 8

Last Updated: 09/26/2026