Yuying Fang

Guangzhou, 510005, China

Last Updated: 09/26/2026

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Found 14 publications

Discovery of furo[2,3-b]isoquinoline derivatives as novel Pks13 inhibitors with reduced hERG inhibition.

Discovery of furo[2,3-b]isoquinoline derivatives as novel Pks13 inhibitors with reduced hERG inhibition.

Journal: Bioorganic & medicinal chemistry letters

Published: November 22, 2025

Novel pyrimido[1,2-a]imidazole derivatives as potent Pks13-TE inhibitors: structure-based virtual screening and rational design.

Novel pyrimido[1,2-a]imidazole derivatives as potent Pks13-TE inhibitors: structure-based virtual screening and rational design.

Journal: RSC medicinal chemistry

Published: October 20, 2025

Novel Indoline Derivatives as Ferroptosis Inhibitors: Synthesis, Biological Evaluation, and Mechanistic Investigation.

Novel Indoline Derivatives as Ferroptosis Inhibitors: Synthesis, Biological Evaluation, and Mechanistic Investigation.

Journal: ChemMedChem

Published: June 13, 2025

Identification of broad-spectrum Mpro inhibitors: a focus on high-risk coronaviruses and conserved interactions.

Identification of broad-spectrum Mpro inhibitors: a focus on high-risk coronaviruses and conserved interactions.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: May 21, 2025

MMP-9 regulates disulphide isomerase activity of TGM2 to enhance fusion glycoprotein-mediated syncytium formation of respiratory syncytial virus.

MMP-9 regulates disulphide isomerase activity of TGM2 to enhance fusion glycoprotein-mediated syncytium formation of respiratory syncytial virus.

Journal: Protein & cell

Published: May 20, 2025

(-)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells.

(-)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells.

Journal: Antioxidants (Basel, Switzerland)

Published: November 05, 2024

Discovery and optimization of 2-(trifluoromethyl)benzimidazole derivatives as novel ferroptosis inducers in vitro and in vivo.

Discovery and optimization of 2-(trifluoromethyl)benzimidazole derivatives as novel ferroptosis inducers in vitro and in vivo.

Journal: European journal of medicinal chemistry

Published: August 30, 2022

Discovery of novel diphenylbutene derivative ferroptosis inhibitors as neuroprotective agents.

Discovery of novel diphenylbutene derivative ferroptosis inhibitors as neuroprotective agents.

Journal: European journal of medicinal chemistry

Published: September 14, 2021

A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway.

A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway.

Journal: Bioorganic chemistry

Published: May 21, 2021

Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases.

Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases.

Journal: Frontiers in pharmacology

Published: January 22, 2021

Synthesis and evaluation of andrographolide derivatives as potent anti-osteoporosis agents in vitro and in vivo.

Synthesis and evaluation of andrographolide derivatives as potent anti-osteoporosis agents in vitro and in vivo.

Journal: European journal of medicinal chemistry

Published: December 01, 2020

Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action.

Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action.

Journal: ACS central science

Published: November 30, 2020

Showing 1-12 of 14

Last Updated: 09/26/2026