Yves Genisson

Toulouse, France

Last Updated: 09/26/2026

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Found 35 publications

From serendipitous reaction discovery to antimycobacterial opportunities: general access to scarcely reported 2-((pyrrolin-5-yl)amino)phenols.

From serendipitous reaction discovery to antimycobacterial opportunities: general access to scarcely reported 2-((pyrrolin-5-yl)amino)phenols.

Journal: Organic & biomolecular chemistry

Published: September 07, 2026

Design of multivalent pharmacological chaperones against Pompe disease via metal-free ligation.

Design of multivalent pharmacological chaperones against Pompe disease via metal-free ligation.

Journal: Organic & biomolecular chemistry

Published: March 04, 2026

Deciphering the anti-Mycobacterium tuberculosis activity of bioinspired lipidic alkynylcarbinols.

Deciphering the anti-Mycobacterium tuberculosis activity of bioinspired lipidic alkynylcarbinols.

Journal: European journal of medicinal chemistry

Published: September 04, 2025

A plug and play approach to structural variations of bio-inspired anticancer lipidic phenyl dialkynylcarbinols.

A plug and play approach to structural variations of bio-inspired anticancer lipidic phenyl dialkynylcarbinols.

Journal: RSC advances

Published: August 29, 2025

Natural and Bioinspired Lipidic Alkynylcarbinols as Leishmanicidal, Antiplasmodial, Trypanocidal, Fungicidal, Antibacterial, and Antimycobacterial Agents.

Natural and Bioinspired Lipidic Alkynylcarbinols as Leishmanicidal, Antiplasmodial, Trypanocidal, Fungicidal, Antibacterial, and Antimycobacterial Agents.

Journal: Journal of natural products

Published: September 20, 2024

Synthesis and biological evaluation of natural Lachnophyllum methyl ester, Lachnophyllum lactone and their synthetic analogs.

Synthesis and biological evaluation of natural Lachnophyllum methyl ester, Lachnophyllum lactone and their synthetic analogs.

Journal: Organic & biomolecular chemistry

Published: September 11, 2024

Multivalent pyrrolidines acting as pharmacological chaperones against Gaucher disease.

Multivalent pyrrolidines acting as pharmacological chaperones against Gaucher disease.

Journal: Bioorganic chemistry

Published: November 14, 2023

Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.

Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids.

Journal: Journal of medicinal chemistry

Published: October 10, 2023

Phosphorus Dendrimers for Metal-Free Ligation: Design of Multivalent Pharmacological Chaperones against Gaucher Disease.

Phosphorus Dendrimers for Metal-Free Ligation: Design of Multivalent Pharmacological Chaperones against Gaucher Disease.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: April 18, 2023

Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis: A Crystallographic and Molecular Modelling Study.

Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis: A Crystallographic and Molecular Modelling Study.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: November 09, 2021

Pharmacological Chaperone Therapy for Pompe Disease.

Pharmacological Chaperone Therapy for Pompe Disease.

Journal: Molecules (Basel, Switzerland)

Published: November 05, 2021

SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species.

SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species.

Journal: eLife

Published: September 15, 2021

Showing 1-12 of 35

Last Updated: 09/26/2026