Zara J. Franklin

Aberdeen, SCT AB252ZD, United Kingdom

Last Updated: 09/26/2026

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Found 17 publications

Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer's disease.

Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer's disease.

Journal: Experimental neurology

Published: September 10, 2024

BACE cleavage of APP does not drive the diabetic phenotype of PLB4 mice.

BACE cleavage of APP does not drive the diabetic phenotype of PLB4 mice.

Journal: Neurobiology of disease

Published: January 29, 2023

Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice.

Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice.

Journal: The Journal of endocrinology

Published: August 19, 2022

Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice.

Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice.

Journal: Biochimie

Published: January 27, 2022

The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.

The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: January 20, 2021

Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection.

Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection.

Journal: Disease models & mechanisms

Published: June 11, 2018

Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta-cell mass.

Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta-cell mass.

Journal: Diabetes, obesity & metabolism

Published: July 04, 2017

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.

Journal: The Journal of endocrinology

Published: March 14, 2016

Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction.

Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction.

Journal: BBA clinical

Published: January 22, 2016

Inhibitory effect of somatostatin on insulin secretion is not mediated via the CNS.

Inhibitory effect of somatostatin on insulin secretion is not mediated via the CNS.

Journal: The Journal of endocrinology

Published: January 30, 2015

Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.

Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models.

Journal: The Journal of endocrinology

Published: July 25, 2014

Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice.

Ablation of glucagon receptor signaling by peptide-based glucagon antagonists improves glucose tolerance in high fat fed mice.

Journal: Peptides

Published: July 04, 2014

Showing 1-12 of 17

Last Updated: 09/26/2026