Zdenek Hodny

Prague, PR, Czech Republic

Last Updated: 09/26/2026

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Found 66 publications

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity.

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity.

Journal: Brain pathology (Zurich, Switzerland)

Published: May 05, 2026

Cellular senescence escape and antiviral response discriminate glioblastoma from lower-grade gliomas.

Cellular senescence escape and antiviral response discriminate glioblastoma from lower-grade gliomas.

Journal: Neuro-oncology advances

Published: March 03, 2026

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

Journal: Bioorganic chemistry

Published: January 14, 2026

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

Journal: Cancer cell international

Published: September 05, 2025

Erratum to "Frentizole derivatives with mTOR inhibiting and senomorphic properties" [Biomed. Pharmacother. 167 (2023) 115600].

Erratum to "Frentizole derivatives with mTOR inhibiting and senomorphic properties" [Biomed. Pharmacother. 167 (2023) 115600].

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 09, 2025

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence.

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence.

Journal: Molecular oncology

Published: December 11, 2024

Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment.

Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment.

Journal: eLife

Published: October 10, 2024

Photothermal induction of pyroptosis in malignant glioma spheroids using (16-mercaptohexadecyl)trimethylammonium bromide-modified cationic gold nanorods.

Photothermal induction of pyroptosis in malignant glioma spheroids using (16-mercaptohexadecyl)trimethylammonium bromide-modified cationic gold nanorods.

Journal: Colloids and surfaces. B, Biointerfaces

Published: June 18, 2024

Tristetraprolin affects invasion-associated genes expression and cell motility in triple-negative breast cancer model.

Tristetraprolin affects invasion-associated genes expression and cell motility in triple-negative breast cancer model.

Journal: Cytoskeleton (Hoboken, N.J.)

Published: April 26, 2024

A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension.

A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension.

Journal: Biotechnology journal

Published: April 11, 2024

Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.

Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.

Journal: ACS pharmacology & translational science

Published: April 02, 2024

Clusterin Deficiency Promotes Cellular Senescence in Human Astrocytes.

Clusterin Deficiency Promotes Cellular Senescence in Human Astrocytes.

Journal: Molecular neurobiology

Published: February 27, 2024

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Last Updated: 09/26/2026