Zdenka Ellederova

Libechov, ST, Czech Republic

Last Updated: 09/26/2026

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Found 35 publications

Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.

Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.

Journal: Experimental eye research

Published: March 27, 2026

Molecular features of a Huntington's disease knock-in minipig.

Molecular features of a Huntington's disease knock-in minipig.

Journal: Disease models & mechanisms

Published: December 17, 2025

Polarized Secretion of Mitochondrial DNA by Retinal Pigment Epithelial cells.

Polarized Secretion of Mitochondrial DNA by Retinal Pigment Epithelial cells.

Journal: Experimental eye research

Published: December 15, 2025

Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.

Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.

Journal: Investigative ophthalmology & visual science

Published: November 13, 2025

Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes.

Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes.

Journal: Disease models & mechanisms

Published: July 28, 2025

Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs.

Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs.

Journal: Investigative ophthalmology & visual science

Published: January 21, 2025

Delivery of Human iPSC-Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells.

Delivery of Human iPSC-Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 03, 2024

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.

Journal: Current eye research

Published: April 26, 2024

The Effects of the Coating and Aging of Biodegradable Polylactic Acid Membranes on In Vitro Primary Human Retinal Pigment Epithelium Cells.

The Effects of the Coating and Aging of Biodegradable Polylactic Acid Membranes on In Vitro Primary Human Retinal Pigment Epithelium Cells.

Journal: Biomedicines

Published: March 06, 2024

Raman spectroscopy of brain and skin tissue in a minipig model of Huntington's disease.

Raman spectroscopy of brain and skin tissue in a minipig model of Huntington's disease.

Journal: Analytical methods : advancing methods and applications

Published: December 18, 2023

CircHTT(2,3,4,5,6) - co-evolving with the HTT CAG-repeat tract - modulates Huntington's disease phenotypes.

CircHTT(2,3,4,5,6) - co-evolving with the HTT CAG-repeat tract - modulates Huntington's disease phenotypes.

Journal: Molecular therapy. Nucleic acids

Published: November 26, 2023

Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care.

Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care.

Journal: Journal of visualized experiments : JoVE

Published: November 28, 2022

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Last Updated: 09/26/2026