Zeger Debyser
Leuven, VLG, Belgium
Last Updated: 09/26/2026
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Found 158 publications
The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency.
Journal: Microbiology spectrum
Published: April 27, 2026
High-Affinity Nanobody Against the LEDGF PWWP Domain Inhibits Chromatin Binding In Vitro.
Journal: Biomolecules
Published: February 06, 2026
Absence of Ledgf in mouse brain affects the Kmt2a/b and polycomb balance, synaptic transmission and motor function.
Journal: Acta neuropathologica communications
Published: August 29, 2025
A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.
Journal: Science advances
Published: November 01, 2024
Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.
Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.
Journal: Biochimica et biophysica acta. Reviews on cancer
Published: October 01, 2024
Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.
Journal: European journal of medicinal chemistry
Published: July 29, 2024
LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.
Journal: Structure (London, England : 1993)
Published: June 02, 2024
BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.
Journal: Nature communications
Published: April 08, 2024
EDITORIAL: Putting HIV in the big sleep with the block-and-lock strategy.
Journal: Current opinion in HIV and AIDS
Published: April 03, 2024
New latency-promoting agents for a block-and-lock functional cure strategy.
Journal: Current opinion in HIV and AIDS
Published: March 08, 2024
The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.
Journal: Cells
Published: November 24, 2023
Pharmacological advances in anti-retroviral therapy for human immunodeficiency virus-1 infection: A comprehensive review.
Journal: Reviews in medical virology
Published: November 13, 2023
Last Updated: 09/26/2026