Zekun Li

State Key Laboratory Of Synthetic Biology
Tianjin, China

Last Updated: 09/26/2026

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Found 22 publications

Manganese Capture-and-Release Vesicles for Cancer Immunotherapy.

Manganese Capture-and-Release Vesicles for Cancer Immunotherapy.

Journal: Advanced materials (Deerfield Beach, Fla.)

Published: March 19, 2026

CLT-003 exerts anti-tumor activity in pancreatic cancer by blocking the PI3K/AKT/HIF-1α pathway.

CLT-003 exerts anti-tumor activity in pancreatic cancer by blocking the PI3K/AKT/HIF-1α pathway.

Journal: Cancer biology & medicine

Published: September 30, 2025

Senescent Cancer-Associated Fibroblasts Drive Early-Stage Lymph Node Metastasis in Pancreatic Cancer through Lactate-Mediated Metabolic-Epigenetic Rewiring.

Senescent Cancer-Associated Fibroblasts Drive Early-Stage Lymph Node Metastasis in Pancreatic Cancer through Lactate-Mediated Metabolic-Epigenetic Rewiring.

Journal: Cancer discovery

Published: September 18, 2025

Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 axis disrupts metabolic-epigenetic crosstalk and suppresses progression in hyperglycolytic breast cancer.

Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 axis disrupts metabolic-epigenetic crosstalk and suppresses progression in hyperglycolytic breast cancer.

Journal: Cancer letters

Published: September 16, 2025

Targeting Mast Cell Activation and MIF-Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer.

Targeting Mast Cell Activation and MIF-Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: June 02, 2025

HCAR2 Orchestrates an Immunosuppressive Niche and Determines Checkpoint Inhibitor Responsiveness in Esophageal Squamous Cell Carcinoma.

HCAR2 Orchestrates an Immunosuppressive Niche and Determines Checkpoint Inhibitor Responsiveness in Esophageal Squamous Cell Carcinoma.

Journal: Biological procedures online

Published: May 11, 2025

Trogocytosis-orchestrated CLDN18.2-"dressed" CD8+ T cells drive pancreatic cancer progression via glucose metabolic reprogramming-induced cytotoxicity debilitation and systematic immune senescence cascade.

Trogocytosis-orchestrated CLDN18.2-"dressed" CD8+ T cells drive pancreatic cancer progression via glucose metabolic reprogramming-induced cytotoxicity debilitation and systematic immune senescence cascade.

Journal: Gut

Published: May 05, 2025

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione-Mediated Stemness Maintenance.

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione-Mediated Stemness Maintenance.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 25, 2025

Targeting GPR34 in damage-associated macrophages enhances anti-tumor immunity and the efficacy of Surufatinib in pancreatic cancer.

Targeting GPR34 in damage-associated macrophages enhances anti-tumor immunity and the efficacy of Surufatinib in pancreatic cancer.

Journal: Signal transduction and targeted therapy

Published: April 16, 2025

Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response.

Coenzyme A mitigates cystine-deprivation-induced ferroptosis by suppressing the iron-starvation response.

Journal: The FEBS journal

Published: February 11, 2025

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma.

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma.

Journal: Nature communications

Published: November 25, 2024

Multicenter evaluation of predictive clinical and imaging factors for pathological response in non-small cell lung cancer patients treated with neoadjuvant chemotherapy and immune checkpoint inhibitors.

Multicenter evaluation of predictive clinical and imaging factors for pathological response in non-small cell lung cancer patients treated with neoadjuvant chemotherapy and immune checkpoint inhibitors.

Journal: Cancer immunology, immunotherapy : CII

Published: October 08, 2024

Showing 1-12 of 22

Last Updated: 09/26/2026