Zenobia C. D'costa

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.

Journal: Gastroenterology
Published: July 27, 2020

TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells.

TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells.

Journal: Oncogene
Published: August 08, 2018

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.

Journal: EMBO molecular medicine
Published: December 10, 2016

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.

Journal: PloS one
Published: October 17, 2016

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.

Journal: Cancer research
Published: October 17, 2016

Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

Journal: Oncotarget
Published: July 22, 2016

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

Journal: Oncotarget
Published: April 20, 2016

The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription.

The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription.

Journal: Oncotarget
Published: April 19, 2016

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma.

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma.

Journal: Oncotarget
Published: September 21, 2015

Development of a potent and selective cell penetrant Legumain inhibitor.

Development of a potent and selective cell penetrant Legumain inhibitor.

Journal: Bioorganic & medicinal chemistry letters
Published: September 10, 2015

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.

Journal: Oncotarget
Published: April 19, 2014

P3 SAR exploration of biphenyl carbamate based Legumain inhibitors.

P3 SAR exploration of biphenyl carbamate based Legumain inhibitors.

Journal: Bioorganic & medicinal chemistry letters
Published: January 30, 2014
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Last Updated: 09/26/2026