Zhang-xu X. He

450046, PR China
Puerto Rico

Last Updated: 09/26/2026

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Found 14 publications

Innovative Medicinal Chemistry Strategies for Improving Target Binding Kinetics in Drug Discovery.

Innovative Medicinal Chemistry Strategies for Improving Target Binding Kinetics in Drug Discovery.

Journal: Journal of medicinal chemistry
Published: October 28, 2025

Design, synthesis, and biological evaluation of novel pyridazinone-based EED inhibitors for prostate cancer.

Design, synthesis, and biological evaluation of novel pyridazinone-based EED inhibitors for prostate cancer.

Journal: European journal of medicinal chemistry
Published: January 18, 2025

Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis.

Formononetin Mitigates Liver Fibrosis via Promoting Hepatic Stellate Cell Senescence and Inhibiting EZH2/YAP Axis.

Journal: Journal of agricultural and food chemistry
Published: October 03, 2024

Discovery of 1,2,4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling.

Discovery of 1,2,4-Triazole-3-thione Derivatives as Potent and Selective DCN1 Inhibitors for Pathological Cardiac Fibrosis and Remodeling.

Journal: Journal of medicinal chemistry
Published: August 19, 2024

Discovery of Novel Imidazo[1,2-a]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect.

Discovery of Novel Imidazo[1,2-a]pyridine-Based HDAC6 Inhibitors as an Anticarcinogen with a Cardioprotective Effect.

Journal: Journal of medicinal chemistry
Published: August 05, 2024

Exploration of detection methods for free silica with different crystal forms in dust

Exploration of detection methods for free silica with different crystal forms in dust

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
Published: March 27, 2024

Targeting cullin neddylation for cancer and fibrotic diseases.

Targeting cullin neddylation for cancer and fibrotic diseases.

Journal: Theranostics
Published: September 13, 2022

Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects.

Discovery of Potent and Selective 2-(Benzylthio)pyrimidine-based DCN1-UBC12 Inhibitors for Anticardiac Fibrotic Effects.

Journal: Journal of medicinal chemistry
Published: December 23, 2021

Current development of CBP/p300 inhibitors in the last decade.

Current development of CBP/p300 inhibitors in the last decade.

Journal: European journal of medicinal chemistry
Published: August 18, 2020

Design, synthesis and biological evaluation of novel thiosemicarbazone-indole derivatives targeting prostate cancer cells.

Design, synthesis and biological evaluation of novel thiosemicarbazone-indole derivatives targeting prostate cancer cells.

Journal: European journal of medicinal chemistry
Published: June 25, 2020

Pyridazine as a privileged structure: An updated review on anticancer activity of pyridazine containing bioactive molecules.

Pyridazine as a privileged structure: An updated review on anticancer activity of pyridazine containing bioactive molecules.

Journal: European journal of medicinal chemistry
Published: June 05, 2020

Pyrimidine: A promising scaffold for optimization to develop the inhibitors of ABC transporters.

Pyrimidine: A promising scaffold for optimization to develop the inhibitors of ABC transporters.

Journal: European journal of medicinal chemistry
Published: March 29, 2020
Showing 1-12 of 14

Last Updated: 09/26/2026