Zhendan Y. He

3688 Nanhai Road
Shenzhen, 518055, China

Last Updated: 09/26/2026

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Found 94 publications

Diversity-enhancing synthesis of novel arylnaphthalene lignan and hexahydrobenzo[k]phenanthridine analogues and identification of a potent antitumor lead.

Diversity-enhancing synthesis of novel arylnaphthalene lignan and hexahydrobenzo[k]phenanthridine analogues and identification of a potent antitumor lead.

Journal: Organic & biomolecular chemistry

Published: August 04, 2026

Design, Synthesis, and Biological Evaluation of Novel PAK1/HDAC10 Dual Inhibitors That Activate Antitumor Immunity for Triple-Negative Breast Cancer Treatment.

Design, Synthesis, and Biological Evaluation of Novel PAK1/HDAC10 Dual Inhibitors That Activate Antitumor Immunity for Triple-Negative Breast Cancer Treatment.

Journal: Journal of medicinal chemistry

Published: July 08, 2026

Design, synthesis, and biological evaluation of selective cytotoxicity-derived Miliusol derivatives inducing profound TNBC regression in vivo.

Design, synthesis, and biological evaluation of selective cytotoxicity-derived Miliusol derivatives inducing profound TNBC regression in vivo.

Journal: Bioorganic & medicinal chemistry

Published: February 06, 2026

Fenticonazole targets NF-κB p105/p50 to suppress triple-negative breast cancer via ROS-mediated ER stress and apoptosis.

Fenticonazole targets NF-κB p105/p50 to suppress triple-negative breast cancer via ROS-mediated ER stress and apoptosis.

Journal: Biochemical pharmacology

Published: November 10, 2025

JR20, a novel natural product-derived compound, exhibits potent anti-biofilm activity against methicillin-resistant Staphylococcus aureus.

JR20, a novel natural product-derived compound, exhibits potent anti-biofilm activity against methicillin-resistant Staphylococcus aureus.

Journal: Frontiers in microbiology

Published: November 10, 2025

Tenuistones A-H, novel flavonoid derivatives from Miliusa tenuistipitata with anti-proliferative and anti-migration activities against triple-negative breast cancer cells.

Tenuistones A-H, novel flavonoid derivatives from Miliusa tenuistipitata with anti-proliferative and anti-migration activities against triple-negative breast cancer cells.

Journal: Bioorganic & medicinal chemistry

Published: July 27, 2025

(+)-Miliusol suppresses the Warburg effect and induces regulated cell death in triple-negative breast cancer through targeting EIF3D and remodeling cancer metabolism.

(+)-Miliusol suppresses the Warburg effect and induces regulated cell death in triple-negative breast cancer through targeting EIF3D and remodeling cancer metabolism.

Journal: Acta pharmaceutica Sinica. B

Published: June 24, 2025

4-Hydroxychalcone Inhibits Human Coronavirus HCoV-OC43 by Targeting EGFR/AKT/ERK1/2 Signaling Pathway.

4-Hydroxychalcone Inhibits Human Coronavirus HCoV-OC43 by Targeting EGFR/AKT/ERK1/2 Signaling Pathway.

Journal: Viruses

Published: June 23, 2025

Fluorescence lifetime imaging microscopy approach reveals quantitative signatures for hepatocellular carcinoma diagnosis.

Fluorescence lifetime imaging microscopy approach reveals quantitative signatures for hepatocellular carcinoma diagnosis.

Journal: Frontiers in oncology

Published: March 23, 2025

Corrigendum to "Therapeutic potential of Moringa oleifera seed polysaccharide embedded silver nanoparticles in wound healing" [Int. J. Biol. Macromol. 184 (2021): 144-158].

Corrigendum to "Therapeutic potential of Moringa oleifera seed polysaccharide embedded silver nanoparticles in wound healing" [Int. J. Biol. Macromol. 184 (2021): 144-158].

Journal: International journal of biological macromolecules

Published: February 05, 2025

Discovery of a Novel Selective PAK1/HDAC6/HDAC10 Inhibitor ZMF-25 that Induces Mitochondrial Metabolic Breakdown and Autophagy-Related Cell Death in Triple-Negative Breast Cancer.

Discovery of a Novel Selective PAK1/HDAC6/HDAC10 Inhibitor ZMF-25 that Induces Mitochondrial Metabolic Breakdown and Autophagy-Related Cell Death in Triple-Negative Breast Cancer.

Journal: Research (Washington, D.C.)

Published: January 15, 2025

Structure, Nuclear Magnetic Resonance Data, Biological Activity, and Synthesis of the Okaramine Family Compounds.

Structure, Nuclear Magnetic Resonance Data, Biological Activity, and Synthesis of the Okaramine Family Compounds.

Journal: Journal of agricultural and food chemistry

Published: January 06, 2025

Showing 1-12 of 94

Last Updated: 09/26/2026