Zhenfan Wen

Nanjing, 210023, China

Last Updated: 09/26/2026

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Found 10 publications

Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway.

Drug-Conjugated Tam-NHC-Gold(I) Complexes Overcome ESR1 Mutant Breast Cancer Resistance and Downregulate the RAMP3/CALCR Signaling Pathway.

Journal: Journal of medicinal chemistry

Published: June 30, 2026

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity.

Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity.

Journal: Angewandte Chemie (International ed. in English)

Published: December 21, 2025

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 14, 2025

Gold(I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR.

Gold(I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR.

Journal: European journal of medicinal chemistry

Published: October 18, 2024

More than just DNA damage: Pt(ΙΙ)-NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death.

More than just DNA damage: Pt(ΙΙ)-NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death.

Journal: European journal of medicinal chemistry

Published: September 26, 2024

Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.

Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: January 23, 2024

Tumor-Targeting NHC-Au(I) Complex Induces Immunogenic Cell Death in Hepatocellular Carcinoma.

Tumor-Targeting NHC-Au(I) Complex Induces Immunogenic Cell Death in Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: February 24, 2023

Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer.

Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer.

Journal: European journal of medicinal chemistry

Published: February 02, 2023

SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.

SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.

Journal: Pharmacological research

Published: November 02, 2022

Recent development of gold(I) and gold(III) complexes as therapeutic agents for cancer diseases.

Recent development of gold(I) and gold(III) complexes as therapeutic agents for cancer diseases.

Journal: Chemical Society reviews

Published: June 14, 2022

Showing 1-10 of 10

Last Updated: 09/26/2026