Zhengsheng Zhan

No. 19A Yuquan Road
Yuquan, 100049, China

Last Updated: 09/26/2026

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Found 16 publications

Discovery of isoindoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.

Discovery of isoindoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents.

Journal: Molecular diversity

Published: October 17, 2025

Dual targeting of VEGFR2 and CSF1R with SYHA1813 confers novel strategy for treating both BRAF wild-type and mutant melanoma.

Dual targeting of VEGFR2 and CSF1R with SYHA1813 confers novel strategy for treating both BRAF wild-type and mutant melanoma.

Journal: Cancer cell international

Published: March 31, 2025

MSCSO: A Modified Sand Cat Swarm Algorithm for 3D UAV Path Planning in Complex Environments with Multiple Threats.

MSCSO: A Modified Sand Cat Swarm Algorithm for 3D UAV Path Planning in Complex Environments with Multiple Threats.

Journal: Sensors (Basel, Switzerland)

Published: March 22, 2025

Incorporation of a rigid 1,3-diketone-containing fragment led to significantly improved AXL inhibitory activity: design, synthesis, and SAR of the anilinopyrimidine AXL inhibitors.

Incorporation of a rigid 1,3-diketone-containing fragment led to significantly improved AXL inhibitory activity: design, synthesis, and SAR of the anilinopyrimidine AXL inhibitors.

Journal: Molecular diversity

Published: October 25, 2024

A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease.

A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease.

Journal: Molecules (Basel, Switzerland)

Published: March 16, 2024

Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect.

Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect.

Journal: MedComm

Published: March 09, 2024

Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives.

Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives.

Journal: Molecular diversity

Published: August 24, 2023

Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma.

Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma.

Journal: Acta pharmaceutica Sinica. B

Published: May 14, 2023

Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase.

Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase.

Journal: Journal of medicinal chemistry

Published: December 16, 2022

Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.

Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.

Journal: Cell discovery

Published: May 09, 2022

Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation.

Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation.

Journal: European journal of medicinal chemistry

Published: September 27, 2020

Synthesis of triazolotriazine derivatives as c-Met inhibitors.

Synthesis of triazolotriazine derivatives as c-Met inhibitors.

Journal: Molecular diversity

Published: December 05, 2019

Showing 1-12 of 16

Last Updated: 09/26/2026