Zhi-dong Zhang

State Key Laboratory Of Metabolism And Regulation In Complex Organisms, State Key Laboratory Of Virology And Biosafety
Wuhan, 430071, China

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 14 publications

LRMDA promotes intestinal mucosal barrier integrity and limits colitis and colon cancer.

LRMDA promotes intestinal mucosal barrier integrity and limits colitis and colon cancer.

Journal: iScience

Published: February 16, 2026

An additional site mutation in MITA/STING gain-of-function mutants abolishes the autoimmune SAVI phenotypes and directs a therapeutic strategy.

An additional site mutation in MITA/STING gain-of-function mutants abolishes the autoimmune SAVI phenotypes and directs a therapeutic strategy.

Journal: Cell insight

Published: December 30, 2025

MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression.

MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression.

Journal: Developmental cell

Published: July 11, 2025

Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115.

Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115.

Journal: Cellular & molecular immunology

Published: September 05, 2023

The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection.

The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection.

Journal: Cell insight

Published: January 16, 2023

The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS.

The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS.

Journal: Nature communications

Published: May 18, 2022

The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel Facilitates Virus Infection Through the Ca2+ -LRMDA Axis in Myeloid Cells.

The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel Facilitates Virus Infection Through the Ca2+ -LRMDA Axis in Myeloid Cells.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: May 15, 2022

Multifaceted Roles of the E3 Ubiquitin Ligase RING Finger Protein 115 in Immunity and Diseases.

Multifaceted Roles of the E3 Ubiquitin Ligase RING Finger Protein 115 in Immunity and Diseases.

Journal: Frontiers in immunology

Published: May 05, 2022

USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network.

USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network.

Journal: Cell insight

Published: April 19, 2022

RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13.

RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: November 23, 2021

Regulation and function of the cGAS-MITA/STING axis in health and disease.

Regulation and function of the cGAS-MITA/STING axis in health and disease.

Journal: Cell insight

Published: September 24, 2021

RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA.

RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA.

Journal: Nature communications

Published: February 10, 2020

Showing 1-12 of 14

Last Updated: 09/26/2026