Zhihao Shu

Changsha, China

Last Updated: 09/26/2026

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Found 19 publications

PACS2 deficiency ameliorates hepatic steatosis via inhibition of the JNK signaling pathway in diabetic mice.

PACS2 deficiency ameliorates hepatic steatosis via inhibition of the JNK signaling pathway in diabetic mice.

Journal: Biochemical pharmacology

Published: November 21, 2025

Cohort Profile: The Hunan Cohort of residents exposed to heavy metals.

Cohort Profile: The Hunan Cohort of residents exposed to heavy metals.

Journal: International journal of epidemiology

Published: May 24, 2024

S1PR3 in hippocampal neurons improves synaptic plasticity and decreases depressive behavior via downregulation of RhoA/ROCK1.

S1PR3 in hippocampal neurons improves synaptic plasticity and decreases depressive behavior via downregulation of RhoA/ROCK1.

Journal: Progress in neuro-psychopharmacology & biological psychiatry

Published: May 12, 2024

S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis.

S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis.

Journal: Journal of biochemical and molecular toxicology

Published: May 10, 2024

Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease.

Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease.

Journal: Journal of medicinal chemistry

Published: March 28, 2024

SRSF3 Inhibits High Glucose and Palmitic Acid-Induced Cardiomyocyte Apoptosis Through the PI3K/AKT and NF-κB Pathways.

SRSF3 Inhibits High Glucose and Palmitic Acid-Induced Cardiomyocyte Apoptosis Through the PI3K/AKT and NF-κB Pathways.

Journal: Journal of biochemical and molecular toxicology

Published: December 28, 2023

S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function.

S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function.

Journal: Life sciences

Published: April 11, 2023

Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.

Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.

Journal: Diabetes & vascular disease research

Published: May 13, 2022

Identifying myoglobin as a mediator of diabetic kidney disease: a machine learning-based cross-sectional study.

Identifying myoglobin as a mediator of diabetic kidney disease: a machine learning-based cross-sectional study.

Journal: Scientific reports

Published: March 18, 2022

AKT/PACS2 Participates in Renal Vascular Hyperpermeability by Regulating Endothelial Fatty Acid Oxidation in Diabetic Mice.

AKT/PACS2 Participates in Renal Vascular Hyperpermeability by Regulating Endothelial Fatty Acid Oxidation in Diabetic Mice.

Journal: Frontiers in pharmacology

Published: February 16, 2022

S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization.

S1PR2/RhoA/ROCK1 pathway promotes inflammatory bowel disease by inducing intestinal vascular endothelial barrier damage and M1 macrophage polarization.

Journal: Biochemical pharmacology

Published: January 02, 2022

Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis.

Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis.

Journal: Journal of medicinal chemistry

Published: September 29, 2020

Showing 1-12 of 19

Last Updated: 09/26/2026