Zhihua Li

Toronto, ON M5G2C1, Canada

Last Updated: 09/26/2026

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Found 10 publications

PIKfyve inhibition in MM disrupts autophagy and lysosome function, increasing MHC expression and cholesterol metabolism.

PIKfyve inhibition in MM disrupts autophagy and lysosome function, increasing MHC expression and cholesterol metabolism.

Journal: Blood
Published: May 21, 2025

Single-cell profiling of multiple myeloma reveals molecular response to FGFR3 inhibitor despite clinical progression.

Single-cell profiling of multiple myeloma reveals molecular response to FGFR3 inhibitor despite clinical progression.

Journal: Cold Spring Harbor molecular case studies
Published: September 30, 2022

Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression.

Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression.

Journal: Nature communications
Published: April 07, 2021

A phase-1 trial of linsitinib (OSI-906) in combination with bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.

A phase-1 trial of linsitinib (OSI-906) in combination with bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.

Journal: Leukemia & lymphoma
Published: January 29, 2021

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma.

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma.

Journal: Leukemia
Published: March 27, 2020

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Journal: Nature communications
Published: July 18, 2016

Identification of human plasma cells with a lamprey monoclonal antibody.

Identification of human plasma cells with a lamprey monoclonal antibody.

Journal: JCI insight
Published: May 07, 2016

Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop.

Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop.

Journal: Cancer research
Published: July 05, 2014

Differential regulation of FGFR3 by PTPN1 and PTPN2.

Differential regulation of FGFR3 by PTPN1 and PTPN2.

Journal: Proteomics
Published: June 06, 2014

A 2,6,9-hetero-trisubstituted purine inhibitor exhibits potent biological effects against multiple myeloma cells.

A 2,6,9-hetero-trisubstituted purine inhibitor exhibits potent biological effects against multiple myeloma cells.

Journal: Bioorganic & medicinal chemistry
Published: February 04, 2013
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Last Updated: 09/26/2026