Zhiyu Hu

State Key Laboratory Of Cellular Stress Biology
Xiamen, 361102, China

Last Updated: 09/26/2026

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Found 13 publications

Discovery of Potent and Selective Pyrrolo[2,3-d]pyrimidine Derivatives as Fourth-Generation EGFR Inhibitors Targeting Triple Mutations.

Discovery of Potent and Selective Pyrrolo[2,3-d]pyrimidine Derivatives as Fourth-Generation EGFR Inhibitors Targeting Triple Mutations.

Journal: Journal of medicinal chemistry

Published: September 09, 2025

Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification.

Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modification.

Journal: Acta pharmaceutica Sinica. B

Published: June 12, 2024

Three nona-2,7-dienoic acid derivatives from saltern derived Micromonospora sp. FXY415.

Three nona-2,7-dienoic acid derivatives from saltern derived Micromonospora sp. FXY415.

Journal: Natural product research

Published: May 03, 2023

Discovery of urea-based pleuromutilin derivatives as potent gram-positive antibacterial agents.

Discovery of urea-based pleuromutilin derivatives as potent gram-positive antibacterial agents.

Journal: Bioorganic chemistry

Published: February 16, 2023

Nigericin is effective against multidrug resistant gram-positive bacteria, persisters, and biofilms.

Nigericin is effective against multidrug resistant gram-positive bacteria, persisters, and biofilms.

Journal: Frontiers in cellular and infection microbiology

Published: September 28, 2022

Pentacyclic Cytochalasins and Their Derivatives from the Endophytic Fungus Phomopsis sp. xz-18.

Pentacyclic Cytochalasins and Their Derivatives from the Endophytic Fungus Phomopsis sp. xz-18.

Journal: Molecules (Basel, Switzerland)

Published: August 15, 2021

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility.

Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility.

Journal: Organic letters

Published: May 28, 2020

Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.

Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.

Journal: European journal of medicinal chemistry

Published: April 10, 2020

Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer.

Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer.

Journal: Cell chemical biology

Published: April 01, 2020

Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors.

Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: November 28, 2019

New 12,8-Eudesmanolides from Eutypella sp. 1-15.

New 12,8-Eudesmanolides from Eutypella sp. 1-15.

Journal: The Journal of antibiotics

Published: June 20, 2016

Aspertetranones A-D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp. ZL0-1b14.

Aspertetranones A-D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp. ZL0-1b14.

Journal: Journal of natural products

Published: September 18, 2015

Showing 1-12 of 13

Last Updated: 09/26/2026