Zhizhou Fang

Frankfurter Str. 250
Darmstadt, HE 64293, Germany

Last Updated: 09/26/2026

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Found 14 publications

Evaluation of the disconnect between hepatocyte and microsomal intrinsic clearance at intracellular and extracellular pH.

Evaluation of the disconnect between hepatocyte and microsomal intrinsic clearance at intracellular and extracellular pH.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: January 29, 2026

Drug-drug interaction assessments of clinical transporter inhibition: Learnings from the Transporter Working Group of the International Consortium for Innovation and Quality in Pharmaceutical Development.

Drug-drug interaction assessments of clinical transporter inhibition: Learnings from the Transporter Working Group of the International Consortium for Innovation and Quality in Pharmaceutical Development.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: November 14, 2025

Precipitation as key parameter for early oral drug absorption predictions, Part I: Acquisition of critical data.

Precipitation as key parameter for early oral drug absorption predictions, Part I: Acquisition of critical data.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: April 25, 2025

Beyond-Rule-of-Five Compounds Are Not Different: In Vitro-In Vivo Extrapolation of Female CD-1 Mouse Clearance Based on Merck Healthcare KGaA Compound Set.

Beyond-Rule-of-Five Compounds Are Not Different: In Vitro-In Vivo Extrapolation of Female CD-1 Mouse Clearance Based on Merck Healthcare KGaA Compound Set.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 14, 2025

In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©.

In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©.

Journal: RSC medicinal chemistry

Published: November 01, 2024

Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.

Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: October 25, 2023

Discovery of quinazoline HPK1 inhibitors with high cellular potency.

Discovery of quinazoline HPK1 inhibitors with high cellular potency.

Journal: Bioorganic & medicinal chemistry

Published: February 23, 2023

Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity.

Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity.

Journal: ChemMedChem

Published: June 22, 2021

Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.

Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: February 07, 2021

Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening.

Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening.

Journal: Pharmaceutical research

Published: March 19, 2020

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Journal: Cell reports

Published: February 17, 2017

Covalent-Allosteric Kinase Inhibitors.

Covalent-Allosteric Kinase Inhibitors.

Journal: Angewandte Chemie (International ed. in English)

Published: March 06, 2015

Showing 1-12 of 14

Last Updated: 09/26/2026