Zhonghua Li

156 Jinshui East Road
Zhengzhou, 450046, China

Last Updated: 09/26/2026

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Found 31 publications

Deep learning-driven discovery and optimization of natural LSD1 inhibitors for the treatment of Alzheimer's disease.

Deep learning-driven discovery and optimization of natural LSD1 inhibitors for the treatment of Alzheimer's disease.

Journal: Bioorganic chemistry

Published: June 09, 2026

Liuwei Dihuang pills attenuates cognitive dysfunction in APP/PS1 mice through restoring mitochondrial homeostasis and activating the IRS/AKT/GSK3β insulin signaling pathway.

Liuwei Dihuang pills attenuates cognitive dysfunction in APP/PS1 mice through restoring mitochondrial homeostasis and activating the IRS/AKT/GSK3β insulin signaling pathway.

Journal: Frontiers in pharmacology

Published: May 08, 2026

Huanglian Jiedu decoction ameliorates Alzheimer's disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes.

Huanglian Jiedu decoction ameliorates Alzheimer's disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes.

Journal: Iranian journal of basic medical sciences

Published: November 11, 2025

Recent development in PDE4D-targeted inhibitors for Alzheimer's disease therapy.

Recent development in PDE4D-targeted inhibitors for Alzheimer's disease therapy.

Journal: European journal of medicinal chemistry

Published: September 27, 2025

Targeting amyloid-β in Alzheimer's disease: A critical analysis of clinical trials and their implications for drug development.

Targeting amyloid-β in Alzheimer's disease: A critical analysis of clinical trials and their implications for drug development.

Journal: Iranian journal of basic medical sciences

Published: September 23, 2025

Structural modification of atractylenolides: synthesis and evaluation of derivatives with potent anti-Aβ aggregation and neuroprotective activities against Alzheimer's disease.

Structural modification of atractylenolides: synthesis and evaluation of derivatives with potent anti-Aβ aggregation and neuroprotective activities against Alzheimer's disease.

Journal: Bioorganic & medicinal chemistry letters

Published: September 04, 2025

Multi-target neuroprotection of Atractylodes macrocephala ethyl acetate extract against Alzheimer's disease: from bioactivity-guided screening to mechanistic validation.

Multi-target neuroprotection of Atractylodes macrocephala ethyl acetate extract against Alzheimer's disease: from bioactivity-guided screening to mechanistic validation.

Journal: Journal of ethnopharmacology

Published: July 10, 2025

Discovery of Atractylenolide Derivatives as Novel LSD1 Inhibitors for the Treatment of Alzheimer's Disease.

Discovery of Atractylenolide Derivatives as Novel LSD1 Inhibitors for the Treatment of Alzheimer's Disease.

Journal: Journal of agricultural and food chemistry

Published: June 05, 2025

Correction to "Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease".

Correction to "Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease".

Journal: Journal of medicinal chemistry

Published: April 11, 2025

Integrated multi-omics analysis and experimental validation reveals the mechanism of tenuifoliside A activity in Alzheimer's disease.

Integrated multi-omics analysis and experimental validation reveals the mechanism of tenuifoliside A activity in Alzheimer's disease.

Journal: Journal of ethnopharmacology

Published: April 02, 2025

Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease.

Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease.

Journal: Journal of medicinal chemistry

Published: January 27, 2025

Unraveling the therapeutic landscape of approved non-peptide macrocycles.

Unraveling the therapeutic landscape of approved non-peptide macrocycles.

Journal: Acta pharmaceutica Sinica. B

Published: December 28, 2024

Showing 1-12 of 31

Last Updated: 09/26/2026