Zhongren Xu

Nanjing, 210023, China

Last Updated: 09/26/2026

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Found 13 publications

Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.

Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.

Journal: Journal of medicinal chemistry

Published: April 24, 2026

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Glabridin-Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 14, 2025

Evaluating indole‑gold(I) based complexes as potential anti lymphoma agents by disrupting the thioredoxin reductase/glutathione peroxidase axis.

Evaluating indole‑gold(I) based complexes as potential anti lymphoma agents by disrupting the thioredoxin reductase/glutathione peroxidase axis.

Journal: Journal of inorganic biochemistry

Published: March 13, 2025

Recent Advances of Metal Complexes in the Treatment of Hepatocellular Carcinoma.

Recent Advances of Metal Complexes in the Treatment of Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: December 16, 2024

Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.

Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: January 23, 2024

A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins.

A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins.

Journal: Chemical communications (Cambridge, England)

Published: January 11, 2024

NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.

NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.

Journal: Journal of medicinal chemistry

Published: June 09, 2023

Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis.

Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis.

Journal: Journal of medicinal chemistry

Published: June 10, 2022

Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.

Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.

Journal: Redox biology

Published: March 02, 2022

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.

Journal: Journal of medicinal chemistry

Published: January 13, 2022

Repurposing of the gold drug auranofin and a review of its derivatives as antibacterial therapeutics.

Repurposing of the gold drug auranofin and a review of its derivatives as antibacterial therapeutics.

Journal: Drug discovery today

Published: October 13, 2021

Discovery of Potential Flavonoid Inhibitors Against COVID-19 3CL Proteinase Based on Virtual Screening Strategy.

Discovery of Potential Flavonoid Inhibitors Against COVID-19 3CL Proteinase Based on Virtual Screening Strategy.

Journal: Frontiers in molecular biosciences

Published: April 30, 2020

Showing 1-12 of 13

Last Updated: 09/26/2026