Zhuoyao Chen
Oxford, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 11 publications
Structure-Guided Optimization of a Molecular Glue Targeting the KBTBD4-HDAC1/2 Complex.
Journal: ChemMedChem
Published: March 26, 2026
Ubiquitin E3 ligase KLHL6 brings exhausted T-cells back into action.
Journal: Immunity & inflammation
Published: January 10, 2026
Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction.
Journal: Angewandte Chemie (International ed. in English)
Published: April 11, 2025
Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment.
Journal: Nature communications
Published: September 12, 2024
Relationship between HLA genetic variations, COVID-19 vaccine antibody response, and risk of breakthrough outcomes.
Journal: Nature communications
Published: September 08, 2023
Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase.
Journal: The Biochemical journal
Published: January 13, 2022
Ubiquitin ligases: guardians of mammalian development.
Journal: Nature reviews. Molecular cell biology
Published: December 14, 2021
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.
Journal: Cell death and differentiation
Published: August 10, 2021
The role of E3 ubiquitin ligases in the development and progression of glioblastoma.
Journal: Cell death and differentiation
Published: July 16, 2020
Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Journal: Structure (London, England : 1993)
Published: August 16, 2018
Showing 1-11 of 11
Last Updated: 09/26/2026