Zimin Chen

State Key Laboratory Of Biotherapy
Chengdu, 610041, China

Last Updated: 09/26/2026

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Found 35 publications

Structural basis of mpox virus A30/H2 subcomplex formation.

Structural basis of mpox virus A30/H2 subcomplex formation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 05, 2026

Structural characterization of Pseudomonas aeruginosa flagellar hook FlgE reveals a novel β-hairpin element involved in inflammatory modulation.

Structural characterization of Pseudomonas aeruginosa flagellar hook FlgE reveals a novel β-hairpin element involved in inflammatory modulation.

Journal: International journal of biological macromolecules

Published: July 19, 2025

Modification of a SARS-CoV-2 spike-RBD targeting nanobody for pH-dependent binding and its chromatographic engineering for purification of WT and variant S-RBDs with mild elution conditions.

Modification of a SARS-CoV-2 spike-RBD targeting nanobody for pH-dependent binding and its chromatographic engineering for purification of WT and variant S-RBDs with mild elution conditions.

Journal: International journal of biological macromolecules

Published: April 24, 2025

LL-37 Inhibits TMPRSS2-Mediated S2' Site Cleavage and SARS-CoV-2 Infection but Not Omicron Variants.

LL-37 Inhibits TMPRSS2-Mediated S2' Site Cleavage and SARS-CoV-2 Infection but Not Omicron Variants.

Journal: Cell proliferation

Published: February 11, 2025

Molecular basis of two broad-spectrum antibodies neutralizing rabies virus and other phylogroup-I lyssaviruses by blocking structural transition between the pleckstrin-homology and fusion domains in the glycoprotein.

Molecular basis of two broad-spectrum antibodies neutralizing rabies virus and other phylogroup-I lyssaviruses by blocking structural transition between the pleckstrin-homology and fusion domains in the glycoprotein.

Journal: International journal of biological macromolecules

Published: January 06, 2025

A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants.

A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants.

Journal: Signal transduction and targeted therapy

Published: November 24, 2024

Structural basis and mode of action for two broadly neutralizing nanobodies targeting the highly conserved spike stem-helix of sarbecoviruses including SARS-CoV-2 and its variants.

Structural basis and mode of action for two broadly neutralizing nanobodies targeting the highly conserved spike stem-helix of sarbecoviruses including SARS-CoV-2 and its variants.

Journal: PLoS pathogens

Published: September 08, 2024

Structures of two lyssavirus glycoproteins trapped in pre- and post-fusion states and the implications on the spatial-temporal conformational transition along with pH-decrease.

Structures of two lyssavirus glycoproteins trapped in pre- and post-fusion states and the implications on the spatial-temporal conformational transition along with pH-decrease.

Journal: PLoS pathogens

Published: August 27, 2024

XBB.1.16-RBD-based trimeric protein vaccine can effectively inhibit XBB.1.16-included XBB subvariant infection.

XBB.1.16-RBD-based trimeric protein vaccine can effectively inhibit XBB.1.16-included XBB subvariant infection.

Journal: MedComm

Published: January 25, 2024

Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials.

Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials.

Journal: Nature communications

Published: September 27, 2023

Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.

Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.

Journal: PLoS pathogens

Published: March 10, 2023

Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.

Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.

Journal: PLoS pathogens

Published: March 10, 2023

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Last Updated: 09/26/2026