Zimu Li

Guangzhou, China

Last Updated: 09/26/2026

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Found 13 publications

Structures and inhibition of the Crimean-Congo haemorrhagic fever virus polymerase.

Structures and inhibition of the Crimean-Congo haemorrhagic fever virus polymerase.

Journal: Nature
Published: November 04, 2025

Structural basis for sarbecovirus Rc-o319 spike adaptation to Rhinolophus cornutus Bat ACE2 and constraints on switching to human ACE2.

Structural basis for sarbecovirus Rc-o319 spike adaptation to Rhinolophus cornutus Bat ACE2 and constraints on switching to human ACE2.

Journal: PLoS pathogens
Published: September 29, 2025

Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.

Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.

Journal: Cell
Published: August 27, 2025

Structures and receptor binding activities of merbecovirus spike proteins reveal key signatures for human DPP4 adaptation.

Structures and receptor binding activities of merbecovirus spike proteins reveal key signatures for human DPP4 adaptation.

Journal: Science advances
Published: July 11, 2025

SARS-related coronavirus S-protein structures reveal synergistic RBM interactions underpinning high-affinity human ACE2 binding.

SARS-related coronavirus S-protein structures reveal synergistic RBM interactions underpinning high-affinity human ACE2 binding.

Journal: Science advances
Published: March 14, 2025

Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses.

Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses.

Journal: Protein & cell
Published: December 23, 2024

Structural Insights into Bortezomib-Induced Activation of the Caseinolytic Chaperone-Protease System in Mycobacterium tuberculosis.

Structural Insights into Bortezomib-Induced Activation of the Caseinolytic Chaperone-Protease System in Mycobacterium tuberculosis.

Journal: Nature communications
Published: November 27, 2024

Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.

Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.

Journal: Nature communications
Published: November 30, 2023

Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants.

Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants.

Journal: Nature communications
Published: September 06, 2023

An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike.

An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike.

Journal: Cell reports
Published: June 22, 2023

Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.

Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.

Journal: Life science alliance
Published: November 02, 2022

Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.

Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.

Journal: Nature communications
Published: June 17, 2022
Showing 1-12 of 13

Last Updated: 09/26/2026