Zinnia P. Guillen-Parra

Pamplona, NC 31009, Spain

Last Updated: 09/26/2026

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Found 46 publications

Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective Analysis.

Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective Analysis.

Journal: The AAPS journal

Published: July 22, 2025

Role of Antidrug Antibodies in Oncolytic Viral Therapy: A Dynamic Modelling Approach in Cancer Patients Treated with V937 Alone or in Combination.

Role of Antidrug Antibodies in Oncolytic Viral Therapy: A Dynamic Modelling Approach in Cancer Patients Treated with V937 Alone or in Combination.

Journal: Clinical pharmacokinetics

Published: July 03, 2025

Design Optimization for Developing Population Pharmacokinetic Models in Critically Ill Children: Application to Teicoplanin, Piperacillin and Meropenem.

Design Optimization for Developing Population Pharmacokinetic Models in Critically Ill Children: Application to Teicoplanin, Piperacillin and Meropenem.

Journal: Clinical pharmacokinetics

Published: May 21, 2025

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors.

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: April 15, 2025

Development and Application of Physiologically-Based Pharmacokinetic Model to Predict Systemic and Organ Exposure of Colorectal Cancer Drugs.

Development and Application of Physiologically-Based Pharmacokinetic Model to Predict Systemic and Organ Exposure of Colorectal Cancer Drugs.

Journal: Pharmaceutics

Published: November 12, 2024

Pharmacodynamic Model of the Hemodynamic Effects of Propofol and Remifentanil and Their Interaction with Noxious Stimulation.

Pharmacodynamic Model of the Hemodynamic Effects of Propofol and Remifentanil and Their Interaction with Noxious Stimulation.

Journal: Pharmaceutics

Published: October 25, 2024

Mechanistic PKPD modeling to describe cytokine release associated with CD3 T-cell engager therapies.

Mechanistic PKPD modeling to describe cytokine release associated with CD3 T-cell engager therapies.

Journal: Frontiers in immunology

Published: July 12, 2024

Disentangling Anti-Tumor Response of Immunotherapy Combinations: A Physiologically Based Framework for V937 Oncolytic Virus and Pembrolizumab.

Disentangling Anti-Tumor Response of Immunotherapy Combinations: A Physiologically Based Framework for V937 Oncolytic Virus and Pembrolizumab.

Journal: Clinical pharmacology and therapeutics

Published: March 03, 2024

Editorial: Innovative pharmacometric approaches to inform drug development and clinical use.

Editorial: Innovative pharmacometric approaches to inform drug development and clinical use.

Journal: Frontiers in pharmacology

Published: August 07, 2023

Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment.

Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment.

Journal: PLoS computational biology

Published: May 23, 2023

A physiologically based pharmacokinetic model for V937 oncolytic virus in mice.

A physiologically based pharmacokinetic model for V937 oncolytic virus in mice.

Journal: Frontiers in pharmacology

Published: April 24, 2023

Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically-Based Modeling.

Assessment of Clinical Response to V937 Oncolytic Virus After Intravenous or Intratumoral Administration Using Physiologically-Based Modeling.

Journal: Clinical pharmacology and therapeutics

Published: January 20, 2023

Showing 1-12 of 46

Last Updated: 09/26/2026