Ziva Zajec

Ljubljana, 1000, Slovenia

Last Updated: 09/26/2026

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Found 15 publications

Antibacterial and antibiofilm activities of novel bacterial topoisomerase inhibitors against Staphylococcus aureus and other clinically relevant pathogens.

Antibacterial and antibiofilm activities of novel bacterial topoisomerase inhibitors against Staphylococcus aureus and other clinically relevant pathogens.

Journal: European journal of medicinal chemistry

Published: March 05, 2026

Designing the DNA-Intercalating Moiety to Improve the Safety and Efficacy of Novel Bacterial Topoisomerase Inhibitors.

Designing the DNA-Intercalating Moiety to Improve the Safety and Efficacy of Novel Bacterial Topoisomerase Inhibitors.

Journal: Journal of medicinal chemistry

Published: February 06, 2026

Catalytic proteasome subunits are heterogeneously active in human platelets with β1i playing a role in signaling and granule release.

Catalytic proteasome subunits are heterogeneously active in human platelets with β1i playing a role in signaling and granule release.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: January 07, 2025

Discovery of new Hsp90-Cdc37 protein-protein interaction inhibitors: in silico screening and optimization of anticancer activity.

Discovery of new Hsp90-Cdc37 protein-protein interaction inhibitors: in silico screening and optimization of anticancer activity.

Journal: RSC advances

Published: August 13, 2024

First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo.

First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo.

Journal: Bioorganic chemistry

Published: August 01, 2024

New Class of Hsp90 C-Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer.

New Class of Hsp90 C-Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer.

Journal: Journal of medicinal chemistry

Published: July 23, 2024

Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders.

Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders.

Journal: European journal of medicinal chemistry

Published: May 23, 2024

Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency.

Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: January 31, 2024

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.

Journal: NPJ precision oncology

Published: December 07, 2022

Catalytic Stereoconvergent Synthesis of Homochiral β-CF3, β-SCF3, and β-OCF3 Benzylic Alcohols.

Catalytic Stereoconvergent Synthesis of Homochiral β-CF3, β-SCF3, and β-OCF3 Benzylic Alcohols.

Journal: ACS organic & inorganic Au

Published: October 11, 2022

Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel Hsp90 C-terminal domain inhibitors against Ewing sarcoma.

Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel Hsp90 C-terminal domain inhibitors against Ewing sarcoma.

Journal: Bioorganic chemistry

Published: September 15, 2022

In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors.

In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors.

Journal: Biomolecules

Published: May 24, 2022

Showing 1-12 of 15

Last Updated: 09/26/2026