Zixuan Ou

Union Hospital
Wuhan, 430022, China

Last Updated: 09/26/2026

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Found 20 publications

Dysregulated methylation‒ubiquitination crosstalk accelerates intervertebral disc degeneration via MED12 destabilization and cGAS/STING activation.

Dysregulated methylation‒ubiquitination crosstalk accelerates intervertebral disc degeneration via MED12 destabilization and cGAS/STING activation.

Journal: The Journal of clinical investigation
Published: June 30, 2026

Author Correction: Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.

Author Correction: Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.

Journal: EMBO molecular medicine
Published: April 24, 2026

Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.

Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity.

Journal: Cell reports. Medicine
Published: January 23, 2026

A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.

A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.

Journal: Cell chemical biology
Published: October 23, 2025

TDP43 cytoplasmic mislocalization initiates mitochondrial dysfunction and intercellular senescence propagation in intervertebral disc degeneration.

TDP43 cytoplasmic mislocalization initiates mitochondrial dysfunction and intercellular senescence propagation in intervertebral disc degeneration.

Journal: Experimental & molecular medicine
Published: October 22, 2025

Metabolically engineered probiotic OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy.

Metabolically engineered probiotic OMVs as nanovaccine mediating sequential immunomodulation for chronic bone infection immunotherapy.

Journal: Cell reports. Medicine
Published: September 23, 2025

Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment.

Customized extracellular vesicles targeting lysosomal biogenesis deliver therapeutic cargo for intervertebral disc degeneration treatment.

Journal: Journal of nanobiotechnology
Published: August 21, 2025

A sonoelectric niche for noninvasive intervertebral disc regeneration via targeted cell cycle modulation.

A sonoelectric niche for noninvasive intervertebral disc regeneration via targeted cell cycle modulation.

Journal: Science advances
Published: August 08, 2025

Advanced bioactive materials and strategies for tendon repair and function restoration.

Advanced bioactive materials and strategies for tendon repair and function restoration.

Journal: Journal of orthopaedic translation
Published: May 09, 2025

Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.

Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: April 23, 2025

Addressing osteoblast senescence: Molecular pathways and the frontier of anti-ageing treatments.

Addressing osteoblast senescence: Molecular pathways and the frontier of anti-ageing treatments.

Journal: Clinical and translational medicine
Published: March 19, 2025

Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.

Extracellular vesicle-based targeted protein degradation platform for multiple extracellular proteins.

Journal: EMBO molecular medicine
Published: November 14, 2024
Showing 1-12 of 20

Last Updated: 09/26/2026