Zongbing Hao

Jiangsu Key Laboratory Of Drug Discovery And Translational Research For Brain Diseases And Department Of Pharmacology
Suzhou, China

Last Updated: 09/26/2026

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Found 18 publications

Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction.

Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction.

Journal: Nature communications
Published: April 25, 2025

Glucosylceramide accumulation in microglia triggers STING-dependent neuroinflammation and neurodegeneration in mice.

Glucosylceramide accumulation in microglia triggers STING-dependent neuroinflammation and neurodegeneration in mice.

Journal: Science signaling
Published: March 26, 2024

Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model.

Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model.

Journal: Cellular and molecular life sciences : CMLS
Published: October 17, 2023

Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis.

Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis.

Journal: Human molecular genetics
Published: June 22, 2023

Bioinformatics and network-based screening and discovery of potential molecular targets and small molecular drugs for breast cancer.

Bioinformatics and network-based screening and discovery of potential molecular targets and small molecular drugs for breast cancer.

Journal: Frontiers in pharmacology
Published: May 12, 2022

The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.

The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.

Journal: Cellular and molecular life sciences : CMLS
Published: April 27, 2022

Autophagy and Polyglutamine Disease.

Autophagy and Polyglutamine Disease.

Journal: Advances in experimental medicine and biology
Published: July 17, 2020

Autophagy and Prion Disease.

Autophagy and Prion Disease.

Journal: Advances in experimental medicine and biology
Published: July 17, 2020

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Journal: Neuroscience bulletin
Published: January 19, 2020

C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.

C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.

Journal: Aging cell
Published: August 02, 2019

DJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo.

DJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo.

Journal: Journal of cellular physiology
Published: December 27, 2018

Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis.

Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis.

Journal: Neuroscience bulletin
Published: December 10, 2018
Showing 1-12 of 18

Last Updated: 09/26/2026