Zonggen Peng

State Key Laboratory Of Bioactive Substances And Function Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 33 publications

Structural Modification of Tranilast against Poxvirus Based on α, β-Unsaturated Acrylamide Covalent Warhead and Confirmation of the Targets and Mode of Action.

Structural Modification of Tranilast against Poxvirus Based on α, β-Unsaturated Acrylamide Covalent Warhead and Confirmation of the Targets and Mode of Action.

Journal: Journal of medicinal chemistry

Published: April 30, 2026

hnRNPC facilitates coronavirus replication by directly binding the frameshift-stimulatory element of viral genomic RNA.

hnRNPC facilitates coronavirus replication by directly binding the frameshift-stimulatory element of viral genomic RNA.

Journal: PLoS pathogens

Published: January 23, 2026

Mitochondria-targeted natural products with potential for the treatment of mitochondria-related diseases.

Mitochondria-targeted natural products with potential for the treatment of mitochondria-related diseases.

Journal: Chinese journal of natural medicines

Published: November 04, 2025

Erratum: Author correction to "Up-regulation of glyclipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication" [Acta Pharm Sin B 9 (2019) 769-781].

Erratum: Author correction to "Up-regulation of glyclipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication" [Acta Pharm Sin B 9 (2019) 769-781].

Journal: Acta pharmaceutica Sinica. B

Published: May 15, 2025

Synthesis and evolution of 16-membered macrolide carrimycin derivatives as a novel class of anti-HCoV-OC43 agents targeting viral FSE RNA.

Synthesis and evolution of 16-membered macrolide carrimycin derivatives as a novel class of anti-HCoV-OC43 agents targeting viral FSE RNA.

Journal: European journal of medicinal chemistry

Published: December 23, 2024

Discovery of Sporachelins by Genome Mining of a Micromonospora Strain.

Discovery of Sporachelins by Genome Mining of a Micromonospora Strain.

Journal: Journal of natural products

Published: November 19, 2024

Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain.

Lycorine esters exert anti-HCoV-OC43 effect through reversibly acylating cysteine residue in the nsp 12 NiRAN domain.

Journal: Bioorganic chemistry

Published: September 20, 2024

Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism.

Berberine dissociates mitochondrial complex I by SIRT3-dependent deacetylation of NDUFS1 to improve hepatocellular glucose and lipid metabolism.

Journal: Science China. Life sciences

Published: July 04, 2024

Acremosides A-G, Sugar Alcohol-Conjugated Acyclic Sesquiterpenes from a Sponge-Derived Acremonium Species.

Acremosides A-G, Sugar Alcohol-Conjugated Acyclic Sesquiterpenes from a Sponge-Derived Acremonium Species.

Journal: Journal of natural products

Published: April 01, 2024

Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2.

Discovery and development of novel 10,12-disubstituted aloperine derivatives against HCoV-OC43 by targeting allosteric site of host TMPRSS2.

Journal: Bioorganic chemistry

Published: February 09, 2024

The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.

The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.

Journal: Bioorganic chemistry

Published: January 14, 2024

Carrimycin inhibits coronavirus replication by decreasing the efficiency of programmed -1 ribosomal frameshifting through directly binding to the RNA pseudoknot of viral frameshift-stimulatory element.

Carrimycin inhibits coronavirus replication by decreasing the efficiency of programmed -1 ribosomal frameshifting through directly binding to the RNA pseudoknot of viral frameshift-stimulatory element.

Journal: Acta pharmaceutica Sinica. B

Published: October 18, 2023

Showing 1-12 of 33

Last Updated: 09/26/2026