Zongtang Xu

Wenzhou, 325027, China

Last Updated: 09/26/2026

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Found 11 publications

Integrative machine learning and single-nucleus transcriptomics reveal MAPK-centered neuronal responses underlying the potential Alzheimer's disease risk of GenX.

Integrative machine learning and single-nucleus transcriptomics reveal MAPK-centered neuronal responses underlying the potential Alzheimer's disease risk of GenX.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Published: April 10, 2026

RVG-targeted extracellular vesicles loaded with echinatin attenuate dopaminergic neurodegeneration via the IGF-2/PI3K/Akt pathway in Parkinson's disease mice.

RVG-targeted extracellular vesicles loaded with echinatin attenuate dopaminergic neurodegeneration via the IGF-2/PI3K/Akt pathway in Parkinson's disease mice.

Journal: Journal of nanobiotechnology

Published: October 13, 2025

Single-cell sequencing analysis and machine learning model reveal aberrant TIM-3 expression in microglia during Alzheimer's disease progression.

Single-cell sequencing analysis and machine learning model reveal aberrant TIM-3 expression in microglia during Alzheimer's disease progression.

Journal: Journal of translational medicine

Published: August 05, 2025

Elevated blood microplastics and their potential association with Parkinson's disease.

Elevated blood microplastics and their potential association with Parkinson's disease.

Journal: Journal of hazardous materials

Published: July 13, 2025

Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.

Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.

Journal: Cellular and molecular life sciences : CMLS

Published: May 17, 2025

MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity.

MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity.

Journal: Cell discovery

Published: January 21, 2025

Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway.

Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway.

Journal: Journal of hazardous materials

Published: December 19, 2024

ATP6V0A1 protects dopaminergic neurons via the autophagy-lysosomal pathway in Parkinson's disease.

ATP6V0A1 protects dopaminergic neurons via the autophagy-lysosomal pathway in Parkinson's disease.

Journal: Neural regeneration research

Published: November 13, 2024

Investigation of the transcriptome and metabolome of the cerebral cortex and testes in Cntnap4-deficient mice.

Investigation of the transcriptome and metabolome of the cerebral cortex and testes in Cntnap4-deficient mice.

Journal: Journal of psychiatric research

Published: November 10, 2024

LncRNA Tug1 Regulates Post-Stroke Microglial Pyroptosis via PINK1/Parkin-Mediated Mitophagy.

LncRNA Tug1 Regulates Post-Stroke Microglial Pyroptosis via PINK1/Parkin-Mediated Mitophagy.

Journal: Inflammation

Published: August 27, 2024

Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.

Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.

Journal: Cellular and molecular life sciences : CMLS

Published: February 15, 2024

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Last Updated: 09/26/2026