Zrinka Kovarik

Zagreb, Croatia

Last Updated: 09/26/2026

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Found 70 publications

Potent inhibition and limited reactivation of human cholinesterases by cholesterol- and quinoline-based oximes.

Potent inhibition and limited reactivation of human cholinesterases by cholesterol- and quinoline-based oximes.

Journal: Toxicology

Published: May 07, 2026

Assessing oxime reactivation efficacy using principal component analysis: Insights from nerve agents inhibited human butyrylcholinesterase.

Assessing oxime reactivation efficacy using principal component analysis: Insights from nerve agents inhibited human butyrylcholinesterase.

Journal: ADMET & DMPK

Published: April 13, 2026

N,N'-dibenzyl imidazolium oximes are potent reactivators of organophosphate-inhibited human butyrylcholinesterase.

N,N'-dibenzyl imidazolium oximes are potent reactivators of organophosphate-inhibited human butyrylcholinesterase.

Journal: European journal of medicinal chemistry

Published: March 23, 2026

Integrative structural and kinetic analysis of the molecular basis for reduced carbamate inhibition in atypical butyrylcholinesterase.

Integrative structural and kinetic analysis of the molecular basis for reduced carbamate inhibition in atypical butyrylcholinesterase.

Journal: Chemico-biological interactions

Published: November 07, 2025

Outlining the A-series of organophosphorus compounds: Cholinesterase inhibition, reactivation, cytotoxicity, and acute toxicity in mice.

Outlining the A-series of organophosphorus compounds: Cholinesterase inhibition, reactivation, cytotoxicity, and acute toxicity in mice.

Journal: Chemico-biological interactions

Published: June 23, 2025

Photochemistry-driven design of small molecule cholinesterase ligands.

Photochemistry-driven design of small molecule cholinesterase ligands.

Journal: Chemico-biological interactions

Published: June 18, 2025

Simplified assessment of acetylcholinesterase inhibition by environmental organophosphorus pesticides.

Simplified assessment of acetylcholinesterase inhibition by environmental organophosphorus pesticides.

Journal: Chemico-biological interactions

Published: June 17, 2025

RS194B oxime mediated AChE-reactivation and protection in lethal sarin and insecticide organophosphate exposed macaques is accompanied by oxime-independent BChE increases; likely a result of liver damage.

RS194B oxime mediated AChE-reactivation and protection in lethal sarin and insecticide organophosphate exposed macaques is accompanied by oxime-independent BChE increases; likely a result of liver damage.

Journal: Chemico-biological interactions

Published: April 17, 2025

The ionizing zwitterionic oxime antidote attenuates gliosis in mice exposed to sarin.

The ionizing zwitterionic oxime antidote attenuates gliosis in mice exposed to sarin.

Journal: Chemico-biological interactions

Published: April 16, 2025

Pan-cancer analysis of acetylcholinesterase (AChE) expression by a data-driven approach: future directions of AChE in cancer neuroscience.

Pan-cancer analysis of acetylcholinesterase (AChE) expression by a data-driven approach: future directions of AChE in cancer neuroscience.

Journal: Chemico-biological interactions

Published: January 30, 2025

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

Journal: Archives of toxicology

Published: November 21, 2024

New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics.

New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics.

Journal: Biomolecules

Published: May 10, 2024

Showing 1-12 of 70

Last Updated: 09/26/2026