Zsolt Nemethy

30-32 Gyömrői Street
Budapest, BU 1103, Hungary

Last Updated: 09/26/2026

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Found 16 publications

Correction to "Discovery of an In Vitro and In Vivo Potent Nicotinic α7 Positive Allosteric Modulator Clinical Candidate Molecule (RGH-857)".

Correction to "Discovery of an In Vitro and In Vivo Potent Nicotinic α7 Positive Allosteric Modulator Clinical Candidate Molecule (RGH-857)".

Journal: Journal of medicinal chemistry

Published: January 19, 2026

Discovery of an In Vitro and In Vivo Potent Nicotinic α7 Positive Allosteric Modulator Clinical Candidate Molecule (RGH-857).

Discovery of an In Vitro and In Vivo Potent Nicotinic α7 Positive Allosteric Modulator Clinical Candidate Molecule (RGH-857).

Journal: Journal of medicinal chemistry

Published: December 29, 2025

Cellular Mechanisms of Cognitive Enhancement: The In Vivo Modulation of the Firing Activity and the Responsiveness of Rat Hippocampal Neurons by Memantine and Alpha7 Nicotinic Acetylcholine Receptor Ligands.

Cellular Mechanisms of Cognitive Enhancement: The In Vivo Modulation of the Firing Activity and the Responsiveness of Rat Hippocampal Neurons by Memantine and Alpha7 Nicotinic Acetylcholine Receptor Ligands.

Journal: ASN neuro

Published: July 18, 2024

Analysis of neuronal activity impairment in iPSC-derived neurons from idiopathic autism patients.

Analysis of neuronal activity impairment in iPSC-derived neurons from idiopathic autism patients.

Journal: iScience

Published: May 15, 2024

Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists.

Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists.

Journal: Journal of medicinal chemistry

Published: February 23, 2024

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

Journal: Journal of medicinal chemistry

Published: November 21, 2023

Contribution of analog signaling to neurotransmitter interactions and behavior: Role of transporter-mediated nonquantal dopamine release.

Contribution of analog signaling to neurotransmitter interactions and behavior: Role of transporter-mediated nonquantal dopamine release.

Journal: Physiological reports

Published: August 31, 2021

Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist.

Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist.

Journal: European journal of pharmacology

Published: May 07, 2021

HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

Journal: European journal of medicinal chemistry

Published: February 26, 2021

Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach.

Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach.

Journal: European journal of medicinal chemistry

Published: October 08, 2020

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists. Part 2. Versatile steroidal carboxamide derivatives.

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists. Part 2. Versatile steroidal carboxamide derivatives.

Journal: Bioorganic & medicinal chemistry letters

Published: May 22, 2019

Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine.

Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine.

Journal: Drug design, development and therapy

Published: September 26, 2018

Showing 1-12 of 16

Last Updated: 09/26/2026