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          Last Updated: 10/31/2025

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          1 clinical trial found

            Phase II Study of Cladribine Plus Idarubicin Plus Cytarabine (ARAC) in Patients With AML, HR MDS, or Myeloid Blast Phase of CML

            Phase II Study of Cladribine Plus Idarubicin Plus Cytarabine (ARAC) in Patients With AML, HR MDS, or Myeloid Blast Phase of CML

            Who is this study for: Adult patients with Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, or Myelodysplastic Syndrome
            Enrollment Status: Recruiting
            Publish Date: May 11, 2025
            Intervention Type: Drug, Other
            Study Drugs: Cladribine, Cytarabine, Gliteritinib, Idarubicin, Midostaurin, Venetoclax
            Study Phase: Phase 2

            Summary: This phase II trial studies how well cladribine, idarubicin, cytarabine, and venetoclax work in patients with acute myeloid leukemia, high-risk myelodysplastic syndrome, or blastic phase chronic myeloid leukemia. Drugs used in chemotherapy, such as cladribine, idarubicin, cytarabine, and venetoclax, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping...

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            Last Updated: 10/31/2025