Zileuton

Last Updated: 04/28/2026

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Found 708 publications

Scoparone alleviates cisplatin-induced acute kidney injury by inhibiting 5-lipoxygenase-mediated ferroptosis.

Scoparone alleviates cisplatin-induced acute kidney injury by inhibiting 5-lipoxygenase-mediated ferroptosis.

Journal: Toxicology and applied pharmacology

Published: March 07, 2026

Zileuton, 5-lipoxygenase blocker, modulates acute inflammatory response in Nile tilapia.

Zileuton, 5-lipoxygenase blocker, modulates acute inflammatory response in Nile tilapia.

Journal: Developmental and comparative immunology

Published: January 03, 2026

Design, synthesis, in vitro, and in silico evaluation of multi-functionalized pyrimidines as potential multitarget-directed anti-inflammatory agents.

Design, synthesis, in vitro, and in silico evaluation of multi-functionalized pyrimidines as potential multitarget-directed anti-inflammatory agents.

Journal: Bioorganic chemistry

Published: November 28, 2025

Inhibiting Arachidonate-5-lipoxygenase expression ameliorates osteoarthritis progression by suppressing ferroptosis via the JAK2/STAT3 signaling pathway.

Inhibiting Arachidonate-5-lipoxygenase expression ameliorates osteoarthritis progression by suppressing ferroptosis via the JAK2/STAT3 signaling pathway.

Journal: Free radical biology & medicine

Published: November 25, 2025

Development of novel salicylic acid derivatives with dual anti-inflammatory and anti-arthritic potentials: synthesis, in vitro bio-evaluation, and in silico toxicity prediction with molecular modeling simulations.

Development of novel salicylic acid derivatives with dual anti-inflammatory and anti-arthritic potentials: synthesis, in vitro bio-evaluation, and in silico toxicity prediction with molecular modeling simulations.

Journal: RSC advances

Published: October 06, 2025

Novel Pyrazole-3-Cyano-2-Pyridinone Hybrids as Multitarget Anti-Inflammatory Agents: Synthesis, Computational Modeling, and Biological Evaluation.

Novel Pyrazole-3-Cyano-2-Pyridinone Hybrids as Multitarget Anti-Inflammatory Agents: Synthesis, Computational Modeling, and Biological Evaluation.

Journal: Drug design, development and therapy

Published: September 28, 2025

Zileuton nanocrystals alter intestinal phase I/II metabolic enzymes and epithelial permeability in a sex-dependent manner.

Zileuton nanocrystals alter intestinal phase I/II metabolic enzymes and epithelial permeability in a sex-dependent manner.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: September 26, 2025

Dual Inhibition of COX-2/5-LOX Through Novel Hybrids of NSAIDs and Peptides: Insights from Molecular Dynamics Simulation and Per-Residue Decomposition.

Dual Inhibition of COX-2/5-LOX Through Novel Hybrids of NSAIDs and Peptides: Insights from Molecular Dynamics Simulation and Per-Residue Decomposition.

Journal: ChemistryOpen

Published: September 25, 2025

Gut microbiota metabolites and key target molecules in allergic rhinitis: a multi-omics study of gut-nose axis regulation via the inflammation-metabolism network.

Gut microbiota metabolites and key target molecules in allergic rhinitis: a multi-omics study of gut-nose axis regulation via the inflammation-metabolism network.

Journal: Frontiers in microbiology

Published: September 10, 2025

Computational and bioactivity investigations of flavonoid fraction from Dodonaea viscosa against oxidative stress and inflammation.

Computational and bioactivity investigations of flavonoid fraction from Dodonaea viscosa against oxidative stress and inflammation.

Journal: Scientific reports

Published: August 20, 2025

Intestinal mast cell-derived leukotrienes mediate the anaphylactic response to ingested antigens.

Intestinal mast cell-derived leukotrienes mediate the anaphylactic response to ingested antigens.

Journal: Science (New York, N.Y.)

Published: August 07, 2025

Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice.

Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice.

Journal: Science (New York, N.Y.)

Published: August 07, 2025

Showing 1-12 of 708

Last Updated: 04/28/2026