Zileuton

Last Updated: 09/26/2026

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Found 722 publications

Effect of 5-lipoxygenase protein expression in malignant breast cancer cells and mechanisms involved in tumor suppression.

Effect of 5-lipoxygenase protein expression in malignant breast cancer cells and mechanisms involved in tumor suppression.

Journal: Journal of toxicology and environmental health. Part A

Published: June 29, 2026

The dual role of leukotrienes in the tumor microenvironment: balancing pro-tumorigenic and anti-tumor immunity.

The dual role of leukotrienes in the tumor microenvironment: balancing pro-tumorigenic and anti-tumor immunity.

Journal: Cancer biology & therapy

Published: June 23, 2026

The ALOX5-Mitochondrial oxidative stress link in quercetin-mediated nasal epithelial barrier protection in allergic rhinitis.

The ALOX5-Mitochondrial oxidative stress link in quercetin-mediated nasal epithelial barrier protection in allergic rhinitis.

Journal: Biochemical and biophysical research communications

Published: June 17, 2026

Editorial Note: Zileuton Improves Memory Deficits, Amyloid and Tau Pathology in a Mouse Model of Alzheimer's Disease with Plaques and Tangles.

Editorial Note: Zileuton Improves Memory Deficits, Amyloid and Tau Pathology in a Mouse Model of Alzheimer's Disease with Plaques and Tangles.

Journal: PloS one

Published: May 20, 2026

Design, synthesis, and biological evaluation of novel pyrimidine-sulfonamide derivatives as multi-targeted COX-2/5-LOX/sEH inhibitors with potential antiproliferative properties.

Design, synthesis, and biological evaluation of novel pyrimidine-sulfonamide derivatives as multi-targeted COX-2/5-LOX/sEH inhibitors with potential antiproliferative properties.

Journal: RSC advances

Published: May 12, 2026

Synthetic heterocyclic scaffolds relevant to human 15-lipoxygenase-2 (h15-LOX-2) inhibition: Scaffold diversity, structure-activity relationships, selectivity challenges, and future directions.

Synthetic heterocyclic scaffolds relevant to human 15-lipoxygenase-2 (h15-LOX-2) inhibition: Scaffold diversity, structure-activity relationships, selectivity challenges, and future directions.

Journal: European journal of medicinal chemistry

Published: May 03, 2026

Exploration and validation of potential diagnostic biomarkers of PANoptosis in periodontitis using bioinformatics approaches.

Exploration and validation of potential diagnostic biomarkers of PANoptosis in periodontitis using bioinformatics approaches.

Journal: Biochemical and biophysical research communications

Published: March 17, 2026

Scoparone alleviates cisplatin-induced acute kidney injury by inhibiting 5-lipoxygenase-mediated ferroptosis.

Scoparone alleviates cisplatin-induced acute kidney injury by inhibiting 5-lipoxygenase-mediated ferroptosis.

Journal: Toxicology and applied pharmacology

Published: March 07, 2026

Computational and artificial intelligence-guided discovery of potential therapeutic candidates targeting Ml0099 protein of Mycobacterium leprae.

Computational and artificial intelligence-guided discovery of potential therapeutic candidates targeting Ml0099 protein of Mycobacterium leprae.

Journal: Computational biology and chemistry

Published: February 22, 2026

Acute plant-derived C18 fatty acid exposure was associated with changes in muscle 5-LOX protein abundance and volatile profiles in triploid rainbow trout (Oncorhynchus mykiss).

Acute plant-derived C18 fatty acid exposure was associated with changes in muscle 5-LOX protein abundance and volatile profiles in triploid rainbow trout (Oncorhynchus mykiss).

Journal: Food chemistry. Molecular sciences

Published: January 13, 2026

Zileuton, 5-lipoxygenase blocker, modulates acute inflammatory response in Nile tilapia.

Zileuton, 5-lipoxygenase blocker, modulates acute inflammatory response in Nile tilapia.

Journal: Developmental and comparative immunology

Published: January 03, 2026

Cassipourol and β-sitosterol from Malva parviflora L.: a mechanistic study of dual anti-inflammatory action against COX/LOX and TNF-α/BCL-2.

Cassipourol and β-sitosterol from Malva parviflora L.: a mechanistic study of dual anti-inflammatory action against COX/LOX and TNF-α/BCL-2.

Journal: Scientific reports

Published: December 12, 2025

Showing 1-12 of 722

Last Updated: 09/26/2026