Linaclotide

Last Updated: 09/26/2026

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Found 461 publications

Efficacy and Safety of Linaclotide in Pediatric Patients of Functional Constipation: A Meta-analysis of Randomized Controlled Trials.

Efficacy and Safety of Linaclotide in Pediatric Patients of Functional Constipation: A Meta-analysis of Randomized Controlled Trials.

Journal: The Annals of pharmacotherapy

Published: September 04, 2026

Evaluating linaclotide for the treatment of irritable bowel syndrome with constipation in children and adolescents.

Evaluating linaclotide for the treatment of irritable bowel syndrome with constipation in children and adolescents.

Journal: Expert opinion on pharmacotherapy

Published: July 09, 2026

Resolving conformational polymorphism in disulfide-rich peptide drugs.

Resolving conformational polymorphism in disulfide-rich peptide drugs.

Journal: Frontiers in chemistry

Published: June 19, 2026

Constipation with bloating: a clinical approach to evaluation and management.

Constipation with bloating: a clinical approach to evaluation and management.

Journal: Annals of medicine

Published: June 19, 2026

Correction: Application of oral sulfate solution combined with linaclotide in bowel preparation for colonoscopy.

Correction: Application of oral sulfate solution combined with linaclotide in bowel preparation for colonoscopy.

Journal: Frontiers in medicine

Published: June 08, 2026

Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.

Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.

Journal: Neurogastroenterology and motility

Published: May 29, 2026

Evaluating linaclotide for the treatment of functional constipation in children and adolescents.

Evaluating linaclotide for the treatment of functional constipation in children and adolescents.

Journal: Expert opinion on pharmacotherapy

Published: May 05, 2026

Efficacy of linaclotide as adjunct for bowel preparation in patients with chronic constipation: a pre-specified analysis of the APPLE trial.

Efficacy of linaclotide as adjunct for bowel preparation in patients with chronic constipation: a pre-specified analysis of the APPLE trial.

Journal: Clinical endoscopy

Published: April 30, 2026

Rapid and comprehensive identification of the metabolic soft spots of peptide drugs with highly cross-linked disulfide bonds by integrating established proteomic workflow with a product ion filtering strategy.

Rapid and comprehensive identification of the metabolic soft spots of peptide drugs with highly cross-linked disulfide bonds by integrating established proteomic workflow with a product ion filtering strategy.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: April 29, 2026

A targeted partial reduction cyanylation strategy coupled with HRMS for accurate disulfide bridge mapping in disulfide rich cyclic peptides.

A targeted partial reduction cyanylation strategy coupled with HRMS for accurate disulfide bridge mapping in disulfide rich cyclic peptides.

Journal: Journal of chromatography. A

Published: April 17, 2026

Trends in the prescription of constipation medications in Japan (fiscal years 2019-2023): A nationwide baseline study prior to the 2023 clinical guidelines.

Trends in the prescription of constipation medications in Japan (fiscal years 2019-2023): A nationwide baseline study prior to the 2023 clinical guidelines.

Journal: Drug discoveries & therapeutics

Published: April 16, 2026

Efficacy and safety of linaclotide plus polyethylene glycol for bowel preparation before colonoscopy in elderly Chinese patients: a systematic review and meta-analysis.

Efficacy and safety of linaclotide plus polyethylene glycol for bowel preparation before colonoscopy in elderly Chinese patients: a systematic review and meta-analysis.

Journal: Frontiers in medicine

Published: March 18, 2026

Showing 1-12 of 461

Last Updated: 09/26/2026