Mebendazole - Latest Advances

Phase 1 study of mebendazole therapy for refractory/progressive or recurrent pediatric brain tumors.

Journal: Neuro-oncology practice

Published: December 29, 2025

Disruption of epidermal growth factor receptor signaling and cytoskeletal dynamics by mebendazole and gefitinib synergistically impairs paracrine cytokine signaling in non-small cell lung cancer and triple-negative breast cancer Cell lines.

Journal: PloS one

Published: October 22, 2025

Preliminary assessment of repurposed mebendazole nano-systems for passive targeting and potential treatment of bone metastasis.

Journal: Pharmaceutical development and technology

Published: October 13, 2025

Development of an Ultrasensitive Monoclonal Antibody-Based Time-Resolved Fluorescence Immunochromatographic Assay for Mebendazole Detection.

Journal: Journal of agricultural and food chemistry

Published: October 10, 2025

"Diagnostic challenges, atypical presentations, and therapeutic implications in ectopic Enterobius vermicularis infections: a global systematic review."

Journal: Diagnostic microbiology and infectious disease

Published: August 29, 2025

Analysis of discrepancy in SNEDDS performance for a "brick dust" mebendazole between in and vitro and in-vivo estimation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Published: August 24, 2025

Girdin silencing enhances mebendazole-mediated anticancer activity: a combinatorial therapeutic strategy for ovarian cancer.

Journal: Medical oncology (Northwood, London, England)

Published: August 23, 2025

Ecotoxicological risk and environmental assessment of mebendazole: A comprehensive study using freshwater snails as non-target species.

Journal: Journal of hazardous materials

Published: July 23, 2025

Molecular Subtypes and Biomarkers of Ulcerative Colitis Revealed by Sphingolipid Metabolism-Related Genes: Insights from Machine Learning and Molecular Dynamics.

Journal: Current issues in molecular biology

Published: July 08, 2025

Evaluating the Efficacy of Mebendazole Repurposing for Ovarian Cancer Therapy Using Optical Coherence Tomography.

Journal: Journal of biophotonics

Published: July 07, 2025

Significant Improvement in Bioavailability and Therapeutic Efficacy of Mebendazole Oral Nano-Systems Assessed in a Murine Model with Extreme Phenotypes of Susceptibility to Trichinella spiralis.

Journal: Pharmaceutics

Published: June 30, 2025

Repurposing the anthelmintic drug mebendazole in combination with radiation therapy in an isocitrate dehydrogenase mutant glioma model.

Journal: Neuro-oncology advances

Published: June 26, 2025