Aliskiren

Last Updated: 04/28/2026

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1 clinical trial found

    Phase 2, Multicenter, Randomized, Open-label, Controlled, 2-arm Cross-over Study to Evaluate the Clinical Efficacy of a Renin Inhibitor, Aliskiren, Compared to an Angiotensin Converting Enzyme Inhibitor, Enalapril, in C3 Glomerulopathy

    Phase 2, Multicenter, Randomized, Open-label, Controlled, 2-arm Cross-over Study to Evaluate the Clinical Efficacy of a Renin Inhibitor, Aliskiren, Compared to an Angiotensin Converting Enzyme Inhibitor, Enalapril, in C3 Glomerulopathy

    Who is this study for: Patients with Glomerulonephritis
    Enrollment Status: Recruiting
    Publish Date: June 22, 2025
    Intervention Type: Drug
    Study Drugs: Aliskiren, Enalapril
    Study Phase: Phase 2

    Summary: The aim of this cross-over trial is to assess aliskiren, a direct renin inhibitor, as a novel treatment to block complement activation in the kidneys and thereby attenuate renal disease and stabilize or improve kidney function and compare it to the currently used treatment with the angiotensin converting enzyme inhibitor, enalapril, in patients with the complement-mediated renal disease C3 glomeru...

    Showing 1-1 of 1

    Last Updated: 04/28/2026